Introduction to Drug Design and Discovery. Molecular Recognition. Ligand-Based Drug Design. Biostructure-Based Drug Design. Drug-Like Properties and Decision Making in Medicinal Chemistry. Chemical Biology. Natural Products in Drug Discovery. In Vivo Imaging in Drug Discovery. Peptide and Protein Drug Design. Prodrugs in Drug Design and Development. Enzyme Inhibitors: Biostructure- and Mechanism-Based Design. Receptors: Structure, Function, and Pharmacology. Ion Channels: Structure and Function. Neurotransmitter Transporters: Structure, Function, and Drug Binding. GABA and Glutamic Acid Receptor and Transporter Ligands. Acetylcholine. Histamine Receptors. Dopamine and Serotonin. Opioid and Cannabinoid Receptors. Neglected Diseases. Anticancer Agents. Targeting Receptor Tyrosine Kinases. Antibiotics.

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Kristian Stromgaard, Povl Krogsgaard-Larsen, Ulf Madsen

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