Section 1 General Principles How drugs act: general principles How drugs act: molecular aspects Method and measurement in pharmacology Absorption and distribution of drugs Drug elimination and pharmokinetics Section 2 Chemical Mediators Chemical mediators and the autonomic nervous system Cholinergic transmission Noradrenergic transmission Other peripheral mediators: 5-hydroxytryptamine and purines Peptides and proteins as mediators Nitric oxide Local hormones, inflammation and allergy Anti-inflammatory and immunosuppressant drugs Section 3 Drugs Affecting Major Organ Systems The heart The vascular system Atherosclerosis and lipoprotein metabolism Haemostasis and thrombosis The haemopoietic system The respiratory system The kidney The gastrointestinal system The endocrine pancreas and the control of blood glucose Obesity The pituitary and adrenal cortex The thyroid The reproductive system Bone metabolism Section 4 The Central Nervous System Chemical transmission and drug action in the central nervous system Amino acid transmitters Other transmitters and modulators Neurodegenerative disorders General anaesthetic drugs Anxiolytic and hypnotic drugs Antipsychotic drugs Drugs used in affective disorders Antiepileptic drugs and centrally acting muscle relaxants Analgesic drugs Central nervous system stimulants and psychotomimetic drugs Drug dependence and drug abuse Local anaesthetics and other drugs that affect ion channels Section 5 Chemotherapy of Infectious and Malignant Disease Basic principles of chemotherapy Cancer chemotherapy Antibacterial drugs Antiviral drugs Antifungal drugs Ant
HP Rang
Professor HP Rang obtained his first degree in Physiology at
University College London, and went on to graduate in Medicine
before moving to the Department of Pharmacology in Oxford. There he
gained a DPhil, and wasappointed to a University Lectureship in
Pharmacology and a Fellowship at Lincoln College, Oxford. He became
Professor and Head of Department at St George's Hospital Medical
School and later at University College London, and he was Director
of the Novartis (formerly Sandoz) Institute for Medical Research,
based at University College. Professor Rang was elected a Fellow of
the RoyalSociety in 1980. Since retiring in 1999, he has worked as
a consultant to pharmaceutical and biotechnology companies. He has
published many research papers, mainly in the fields of receptor
pharmacology and neuroscience.
With Dr Maureen Dale he wrote the first edition of Pharmacology
(1987),and Professor Jim Ritter became a co-author for the third
and subsequent editions. He is currently preparing a new book on
Drug Discovery, to be published by Harcourt.
MM Dale
Dr Dale is Senior Teaching Fellow in the Department of Pharmacology
of the University of Oxford. Having graduated in Medicine at the
University of the Witwatersrand in Johannesburg, South Africa, she
worked as a medical officer at a Health Centre for several years
before joining the staff of medical school of the University of
Natal. There she was responsible for establishing ab initio, the
first course in experimental/clinical pharmacology in South Africa.
Finding herself in profound disagreement with the 'apartheid'
government in South Africa, she emigrated to the UK where she
joined the Department of Pharmacology of University College London.
There she gained a PhD in pharmacology and was, for many years,
responsible for running the pharmacology course for medical
students and the immunopharmacology course for final year science
students.
Dr Dale has been an editor of the British Journal of Pharmacology.
Before retiring fromUCL in 1991, her research areas were the
immunopharmacology of asthma and rheumatoid arthritis.
JM Ritter
Professor Jim Ritter is Head of the Department of Clinical
Pharmacology at Guy's King's and St Thomas' School of Medicine
(King's College, London, UK). His first degree was in Animal
Physiology and he obtained a D Phil in Pharmacology before
completing clinical medicine at the Radcliffe Infirmary (Oxford).
His basic medical training was in Oxford, London and the Johns
Hopkins Hospital (Baltimore, USA), where he was chief resident for
two years. Subsequent specialist training in clinical pharmacology
was at Hammersmith Hospital (London). He is an honorary consultant
physician at Guy's and St Thomas' NHS Trust where he shares in the
acute general medical take, and sees outpatients in the
hypertension and vascular disease prevention clinics. His research
is in human vascular pharmacology, especially of
endothelium-derived mediators. He sat on the sub-committee on
safety and efficacy of CSM, has chaired local and multicentre
research ethics committees, and currently chairs the Thames
Specialty Training Committee in Clinical Pharmacology. He is one of
the two editors of the British Journal of Clinical Pharmacology.
"Rang & Dale are now due more praise for their new improved version of Pharmacology. As before the writing is excellent and surely undergraduates can master a subject when it is explained so lucidly and with evident enthusiasm. As a comprehensive textbook for pharmacy or pharmacology students it has few rivals. As a guide to help continuing education in modern pharmacology it should be both useful and enjoyable." British Journal of Hospital Medicine
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