Promotional Information

This book covers a variety of cutting-edge basic and clinical PAK research ranging from laboratory benches to hospital beds.

Table of Contents

1. Functional Maturation of PAKs2. Oncogenicity of PAKs and Their Substrates3. Natural or Synthetic Therapeutics that Block PAKs4. PAK1 in Parasites-Host Interaction5. PAK1 in Brain Diseases6. PAK1 in Alzheimer’s and Huntington’s diseases7. PAK1 Controls the Lifespan8. PAK 4-6 in Cancer and Neuronal Development

Reviews

"Here neurologists and other biomedical researchers explain in some detail how PAKs — particularly the oncogenic kinases PAK1 and PAK4 and their blockers — may control various aspects of life and health, and how mammalian PAKs have functionally evolved from their ancestral origins in unicellular organisms such as yeast and amoebas through a series of mutations over millions of years." --Reference and Research Book News, August 2013