Table of Contents

Section one: Introduction 1. Basic concepts and components of the immune system 2. Basic concepts Section two: Antigen-recognition molecules 3. Introduction to antigen recognition 4. Antigens and antibody structure 5. Antibody-antigen interaction 6. Antibody diversity 7. The T cell receptor 8. Major histocompatibility complex 9. Review of antigen recognition Section three: Physiology 10. Antigen processing and presentation 11. Lymphocyte activation 12. Hematopoiesis 13. The organs and tissues of the immune system 14. B cell development 15. T cell development 16. Cell-cell interaction in generating effector lymphocytes 17. Immunological memory 18. Review of immune physiology Section four: Innate Immunity 19. Constitutive defenses including complement 20. Phagocytes 21. Killing in the immune system 22. Inflammation 23. Review of innate immunity Section five: Immune system in health and disease 24. Infections and vaccines 25. Hypersensitivity reactions 26. Immediate hypersensitivity (type I): allergy 27. Autoimmunity 28. Antibody-mediated hypersensitivity (type II) 29. Immune complex disease (type III hypersensitivity) 30. Delayed hypersensitivity (type IV) 31. Primary immunodeficiency 32. Secondary immunodeficiency 33. Transplantation 34. Tumor immunology 35. Immunotherapies 36. Review of immunity in health and disease Appendices Glossary Index