Table of Contents

I. Background.- 1 An Introduction to Seizures and Epilepsy: Cellular Mechanisms Underlying Classification and Treatment.- 2 History and Origin of the Ketogenic Diet.- II. Clinical Aspects.- 3 The Ketogenic Diet: The Physician’s Perspective.- 4 Clinical Use of the Ketogenic Diet: The Dietitian’s Role.- 5 How to Maintain and Support a Ketogenic Diet Program: A Nursing Perspective.- 6 Efficacy of the Ketogenic Diet.- 7 The Ketogenic Diet in Adults.- 8 Indications and Contraindications of the Ketogenic Diet.- 9 Complications of the Ketogenic Diet.- 10 Measuring and Interpreting Ketosis and Fatty Acid Profiles in Patients on a High-Fat Ketogenic Diet.- 11 Insights From Neuroimaging Studies Into Ketosis and the Ketogenic Diet.- 12 Potential Applications of the Ketogenic Diet in Disorders Other Than Epilepsy.- 13 Dietary Treatments for Epilepsy Other Than the Ketogenic Diet.- III. Basic Science Perspectives.- 14 Effects of the Ketogenic Diet on Cerebral Energy Metabolism.- 15 The Ketogenic Diet: Interactions With Brain Amino Acid Handling.- 16 Molecular Regulation of Ketogenesis.- 17 The Effects of Ketone Bodies on Neuronal Excitability.- 18 Effects of the Ketogenic Diet on Acute Seizure Models.- 19 Caloric Restriction and Epilepsy: Historical Perspectives, Relationship to the Ketogenic Diet, and Analysis in Epileptic EL Mice.- 20 The Role of Norepinephrine in the Anticonvulsant Mechanism of Action of the Ketogenic Diet.- 21 Galanin and Neuropeptide Y: Orexigenic Neuropeptides Link Food Intake, Energy Homeostasis, and Seizure Susceptibility.- 22 The Neuroprotective and Antiepileptogenic Effects of the Ketogenic Diet.- Afterword: A Parent’s Perspective on Childhood Epilepsy: The Things I Wish They Had Told Us.- Epilogue.- Appendix A: The Carbohydrate and Caloric Contentof Drugs.- Appendix B: Ketogenic Diet Resources.

Reviews

Foreword by Philip A. Schwartzkroin, PhD
"This book is a comprehensive summary of the use of the ketogenic diet for treatment of medically intractable epilepsy. This book should be read by all those caring for patients with medically intractable epilepsy, and should be on the shelves of all those involved in supervising the ketogenic diet."-The Lancet