The End of Alzheimer's Program


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About the Author

Dale E. Bredesen, M.D., is internationally recognized as an expert in the mechanisms of neurodegenerative diseases such as Alzheimer's disease, and the author of the New York Times bestsellers The End of Alzheimer's (Avery, 2017) and The End of Alzheimer's Program (Avery, 2020), as well as The First Survivors of Alzheimer’s (Avery, 2021). He has held faculty positions at UC San Francisco, UCLA, and the University of California San Diego, and directed the Program on Aging at the Burnham Institute before coming to the Buck Institute for Research on Aging in 1998 as its founding president and CEO. He is currently a professor at UCLA.


“Although the source of the quote ‘The definition of insanity is doing the same thing over and over again and expecting a different result’ has been questioned, its relevance to the pursuit of a single drug approach to the treatment of Alzheimer’s disease is unquestionable. Sanity now prevails with Dr. Bredesen’s challenge to the status quo that may well bring an end to Alzheimer’s disease.”
­–David Perlmutter, MD, from the foreword

“Once in a generation a book comes along that changes the way we think, that sheds light on our darkest struggles, that provides a clear, scientific path to ending the scourge of a disease that robs millions of their minds. The End of Alzheimer’s Program is that book. Whether you want to enhance and optimize your brain at any age, prevent cognitive decline and even reverse early dementia, Dr. Bredesen, in breathtakingly simple, scientifically profound steps maps a way to achieve this. If you have a brain, read this book.”
–Mark Hyman, MD, Head of Strategy and Innovation: Cleveland Clinic Center for Functional Medicine, #1 New York Times bestselling author of Food Fix: How to Save Our Health, Our Economy, Our Communities and Our Planet – One Bite at a Time

“Dale Bredesen MD has done it again. Teaming up with his wife, an integrative physician, and Julie Gregory, one of his recovered patients, he delivers the essential how-to guide for risk reduction and potentially reversal of cognitive decline and Alzheimer’s disease. This elegantly written, step-by-step handbook to Dr. Bredesen’s revolutionary protocol will help thousands if not millions. I give it my highest recommendation.”
–Sara Gottfried, MD, New York Times bestselling author of The Hormone Cure

“This is THE book to be read by anyone interested in how to prevent Alzheimer’s disease. Dr. Bredesen is a world-class neuroscientist, neurologist who brings his expansive experience and brilliance together to provide the best that science has to offer in the prevention of this disease.”
–Dr. Jeffrey Bland, author of Disease Delusion and Founder, Institute for Functional Medicine
“Alzheimer’s disease remains a disease of bleak outlook for most.  However, in The End of Alzheimer’s Program, Dale Bredesen describes new hope based on his decades of research and recent clinical success. This book is an essential tool for anyone who wants to prevent cognitive decline due the ravages of Alzheimer's disease.”
–Terry Wahls, MD, author of The Wahls Protocol A Radical New Way To Treat All Chronic Autoimmune Conditions Using Paleo Principles 

“Alzheimer’s disease is a chronic pandemic that has claimed the lives of millions. In The End of Alzheimer’s Program, Dr. Dale Bredesen offers hope based on his decades of research and recent clinical success, with an emphasis on lifestyle factors including sleep, diet, stress, and movement. COVID-19 has ushered in a new era of resilience and disease prevention, and this book offers the very tools and guidelines we all need to stem the rising tide of Alzheimer’s disease.”
–Arianna Huffington, Founder & CEO, Thrive Global

"I have had the pleasure of knowing and even sharing patients with Dr. Bredesen for several years. In his new book, The End of Alzheimer's Program, Dr. Bredesen modestly and comprehensively sets out the steps to prevent and reverse all stages of cognitive decline. But, please don't let the book's title fool you; the book should be more aptly named The End of All Diseases Program! Because, in its pages, you will find an approachable, useable, doable plan to literally prevent and/or reverse almost all diseases brought on by our modern lifestyle and diet. Read and follow his recommendations and enjoy the ride of a lifetime in good health!"
–Steven R. Gundry MD, Medical Director, The Centers for Restorative Medicine, Four Time NYT's bestselling author of The Plant Paradox Series and The Longevity Paradox

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