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Visualization in Biomedical Computing
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This book constitutes the refereed proceedings of the 4th International Conference on Visualization in Biomedical Computing, VBC '96, held in Hamburg, Germany, in September 1996. The 73 revised full papers presented were selected from a total of 232 submissions. The book reports the state of the art in the field of computer based visualization in medicine and biology. The papers are organized in sections on visualization; image processing; segmentation; registration; brain: description of shape; brain: characterization of pathology; brain: visualization of function; simulation of surgery and endoscopy; image guided surgery and endoscopy.
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Table of Contents

GI tract unraveling in volumetric CT.- Segmentation of the visible human for high quality volume based visualization.- Illustrating anatomic models - A semi-interactive approach.- A fast rendering method using the tree structure of objects in virtualized bronchus endoscope system.- An optimal ray traversal scheme for visualizing colossal medical volumes.- A direct multi-volume rendering method. Application to visual assessment of 3-D image registration algorithms.- Visualization of tissue elasticity by magnetic resonance elastography.- Accurate vessel depiction with phase gradient algorithm in MR angiography.- Visualization and labeling of the Visible Human (TM) dataset: Challenges & resolves.- Rebuilding the visible man.- Image quality improvements in volume rendering.- Real-time merging of visible surfaces for display and segmentation.- Cortical peeling: CSF/grey/white matter boundaries visualized by nesting isosurfaces.- Enhancement of MR images.- Radiometric correction of color cryosection images for three-dimensional segmentation of fine structures.- 3D reconstruction of cerebral vessels and pathologies from a few biplane digital angiographies.- Robust 3-D reconstruction and analysis of microstructures from serial histologic sections, with emphasis on microvessels in prostate cancer.- An extensible MRI simulator for post-processing evaluation.- Compensation of spatial inhomogeneity in MRI based on a parametric bias estimate.- Analysis of coupled multi-image information in microscopy.- Bias field correction of breast MR images.- Region-growing based feature extraction algorithm for tree-like objects.- Scale-space boundary evolution initialized by cores.- Fast, accurate, and reproducible live-wire boundary extraction.- Automatic segmentation of cell nuclei from confocal laser scanning microscopy images.- Evaluation of segmentation algorithms for intravascular ultrasound images.- Fast algorithms for fitting multiresolution hybrid shape models to brain MRI.- Computer aided screening system for lung cancer based on helical CT images.- Unsupervised regularized classification of multi-spectral MRI.- Using an entropy similarity measure to enhance the quality of DSA images with an algorithm based on template matching.- Automatic segmentation of the brain in MRI.- Image analysis using modified self-organizing maps: Automated delineation of the left ventricular cavity boundary in serial echocardiograms.- Analyzing and predicting images through a neural network approach.- An artificial intelligence approach for automatic interpretation of maxillofacial CT images.- Fast Fluid Registration of medical images.- A robust point matching algorithm for autoradiograph alignment.- Registration updating using marker pins in a video based neurosurgical guidance system (VISLAN).- Point-based elastic registration of medical image data using approximating thin-plate splines.- Cortical constraints for non-linear cortical registration.- Image guided microscopic surgery system using mutual-information based registration.- Cross validation of three inter-patients matching methods.- A new approach to fast elastic alignment with applications to human brains.- Individualizing anatomical atlases of the head.- Mutual information for automated multimodal image warping.- Morphological analysis of brain structures using spatial normalization.- Three dimensional MR-based morphometric comparison of schizophrenic and normal cerebral ventricles.- Application of an automatically built 3D morphometric brain atlas: Study of cerebral ventricle shape.- Visualization and mapping of anatomic abnormalities using a probabilistic brain atlas based on random fluid transformations.- L-systems for three-dimensional anatomical modelling: Towards a virtual laboratory in anatomy.- Hierarchical data representation of lung to model morphology and function.- Visualizing group differences in outline shape: Methods from biometrics of landmark points.- Visualising cerebral asymmetry.- Assessing patterns and rates of brain atrophy by serial magnetic resonance imaging: A segmentation, registration, display and quantification procedure.- Characterisation and classification of brain tumours in three-dimensional MR image sequences.- Automatic quantification of multiple sclerosis lesion volume using stereotaxic space.- 3D skeleton for virtual colonoscopy.- Identifying hypometabolism in PET images of the brain: Application to epilepsy.- Multi-array EEG signals mapped with three dimensional images for clinical epilepsy studies.- Visualisation of pain by magnetoencephalography in humans.- Visualization of cat auditory cortical functional organization after electrical stimulation with a multichannel cochlear implant by means of optical imaging.- The brain bench: Virtual stereotaxis for rapid neurosurgery planning and training.- A flexible environment for image guided virtual surgery planning.- An advanced system for the simulation and planning of orthodontic treatments.- Assessment of several virtual endoscopy techniques using computed tomography and Perspective Volume Rendering.- Surgery Simulation using Fast Finite Elements.- Real time volumetric deformable models for surgery simulation.- Craniofacial surgery simulation.- Creation and validation of patient specific anatomical models for prostate surgery planning using virtual reality.- Use of shape for automated, optimized 3D radiosurgical treatment planning.- MRI guided intranasal flexible micro-endoscopy.- Computer-assisted insertion of pedicle screws.- PROBOT - A computer integrated prostatectomy system.- Towards performing ultrasound-guided needle biopsies from within a head-mounted display.- Automated multimodality registration using the full affine transformation: Application to MR and CT guided skull base surgery.

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