Novel Molecular Approaches to Anti-Inflammatory Therapy
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Eosinophil chemoattractants generated in vivo.- Chemokines and their role in human disease.- Structure/function analysis of human interleukin 5 and its receptor.- Potential phospholipase A2s involved in inflammatory diseases.- Mediation of inflammation by cyclooxygenase-2.- Secretory phospholipase A2 inhibitors. Possible new anti-inflammatory agents.- Recent insights into the structure, function and biology of cPLA2.- Control of inflammatory processes by cell-impermeable inhibitors of phospholipase A2.- Leukocyte adhesion and the anti-inflammatory effects of leukocyte integrin blockade.- ANTI-ICAM in inflammatory disease.- Complementary peptides as recognition molecules.- Nitric oxide-releasing NSAIDs: A novel class of GI-sparing anti-inflammatory drugs.- Anti-inflammatory lipocortin-derived peptides.- Inhibition of lipid mediator biosynthesis in human inflammatory cells by BIRM 270.- The use of anti-PECAM reagents in the control of inflammation.- Selective inhibitors of COX-2.- New frontiers in the pharmacotherapy of inflammation.

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