Table of Contents

Preface

Section I: Molecular and Cellular Mechanisms
Ch1. Overview: Cellular Components of the Nervous System and Disease Mechanisms
Ch2. Organization of the Cell Membranes
Ch3. Intracellular Signaling
Ch4. DNA: Epigenetic Control of Transcription and Repair Mechanisms
Ch5. RNA Metabolism and Control of Translation
Ch6. Proteostasis
Ch7. Vesicular Trafficking
Ch8. Cytoskeleton
Ch9. Axonal Transport
Ch10. Axon and Myelin
Ch11. Mitochondria and Energy Metabolism
Ch12. Mechanisms of Cell Death and Axonal Degeneration
Ch13. Growth Factors, Survival, and Regeneration

Section II: Excitability, Signal Communication, and Plasticity
Ch14. Ion Channels and Channelopathies
Ch15. Principles of Synaptic Transmission and Presynaptic Synaptopahies
Ch16. Neurotransmission, Neuromodulation, and Plasticity
Ch17. Glutamatergic Transmission, Plasticity and Synaptopahies
Ch18. Inhibitory Amino Acid Transmission and Synaptopahies
Ch19. Cholinergic Transmission
Ch20. Monoaminergic Neurotransmission

Section III: Microenvironment and Mechanisms of Injury and repair
Ch21. Astrocyte-Neuron Interactions
Ch22. Neuronal Microenvironment
Ch23. Microglia and Inflammation in the Nervous System

Section III: Neuronal Interactions in Cortical and Subcortical Circuits
Ch24. Neocortical Circuits
Ch25. Hippocampal and Amygdala Circuits
Ch26. Thalamocortical Interactions
Ch27. Sleep
Ch28. Behavioral State Control
Ch29. Sensory Processing
Ch30. Cortical Motor Control
Ch31. Segmental Spinal Motor Control
Ch32. Brainstem Motor Control
Ch33. Cerbellum
Ch34. Basal ganglia

Section V: Homeostatic Systems
Ch35. Nociceptors
Ch36. Central Pain Processing and Modulation
Ch37. Autonomic Nervous System
Ch38. Forebrain Control of Homeostasis and Adaptation

Section VI: Cortical Networks and Cognitive Domains
Ch39. Emotion and Social Cognition
Ch40. Episodic Memory, Navigation, and Inner Thoughts
Ch41. Language, Speech, and Semantic Cognition
Ch42. Cortical Executive Networks and High-level Behavioral and Cognitive Control

About the Author

Eduardo E. Benarroch
Professor of Neurology
Department of Neurology, Mayo Clinic, Rochester, MN

Reviews

"The neurologist is increasingly called upon to know the physiological basis of disease, so as to provide better care for patients. As science advances, such knowledge can seem out of reach or arcane, inaccessible to many. And here is where Professor Benarroch's volume excels, by bringing modern scientific understanding, in a clear, concise manner to the reader, whether a student, clinical trainee, or established clinician. This superb volume will serve as an
introduction to the pathophysiology of some disorders for many and, equally, a refresher or update to those seeking such. And for those wishing to dip into the primary literature, it's difficult to
imagine a more satisfying jumping-off volume. Neuroscience for Clinicians fills an important gap in our literature." -- Robert A. Gross, MD, PhD, Professor of Neurology and of Pharmacology & Physiology, University of Rochester Medical Center, Rochester, NY