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Mechanisms of Vascular Disease
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This textbook provides an up-to-date account of the mechanisms and pathophysiology of vascular disease, and the current treatment options open to vascular surgeons. As the scientific basis of vascular disease advances rapidly, it is critical that clinicians have access to relevant information written specifically for vascular surgeons. This account reviews the impact of these scientific advances on established and emerging treatment options. Experts from Australia, North America and Europe have contributed to basic topics such as atherosclerosis, restenosis, thrombosis and haemostasis, ischaemia-reperfusion injury, sepsis, vascular haemodynamics and wound healing. More applied topics such as pain syndromes in vascular surgery and the diabetic foot are also covered in this textbook. This will be a core text for all vascular surgical trainees and is especially appropriate for advanced trainees and consultants wishing to refresh their knowledge base.
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Table of Contents

1. The vascular endothelium: structure and function V. Limaye and M. Vadas; 2. Vascular smooth muscle cells: structure and function Philip Chan; 3. Vascular haemodynamics Michael Lawrence-Brown, Kurt Liffman and James Semmens; 4. Haemostasis: a clinician's perspective Douglas Coghlan and Donald J. Adam; 5. Hypercoagulability and vascular disease Stella Vig; 6. The role of platelets in vascular disease Paul D. Hayes and Natalie J. Hayes; 7. Atherosclerosis Qingbo Xu; 8. Mechanisms of plaque rupture K. J. Molloy and I. M. Loftus; 9. Current and emerging therapies in atheroprotection Stephen J. Nicholls and Philip J. Barter; 10. Molecular approaches to revascularization in peripheral vascular disease Mark J. Mccarthy and Nicholas P. J. Brindle; 11. Raynaud's phenomenon: the vasculitides and fibromuscular dysplasia Dean Patterson, Donald J. Adam, Robert A. Fitridge and Jill Belch; 12. Vascular biology of restenosis Richard D. Kenagy; 13. Restenosis: treatment options current and future John Bingley, Julie Campbell, Gordon Campbell and Philip Walker; 14. Pathogenesis of abdominal aortic aneurysms: a review J. Evans and M. M. Thompson; 15. Remodelling and AAA Janet Powell; 16. Pharmacological treatment of aneurysms J. Evans, J. T. Powell and M. M. Thompson; 17. SIRS, sepsis and multi-organ failure in vascular surgery J. I. Spark; 18. Pathophysiology of reperfusion injury P. A. Cowled, P. E. Laws, D. M. Roach and R. A. Fitridge; 19. Compartment syndromes Matthew Bown and Robert Sayers; 20. Pathophysiology of pain Stephan A. Schug, Helen C. S. Daly and Kathryn J. D. Stannard; 21. Post amputation pain syndromes Stephan A. Schug and Gail Gillespie; 22. Treatment of neuropathic pain Stephan A. Schug and Kathryn J. D. Stannard; 23. Principles of wound healing Gregory S. Schultz, Gloria A. Chin, Lyle Moldawer and Robert F. Diegelmann; 24. Varicose veins: principles and vascular biology Rachel C. Sam, Stanley H. Silverman and Andrew W. Bradbury; 25. Chronic venous insufficiency and leg ulceration: principles and vascular biology Michael Stacey; 26. Pathophysiology and principles of management of the diabetic foot Michael Stacey and Robert Fitridge; 27. Lymphodema: principles, genetics and pathophysiology Tahir Ali and Kevin Burnand; 28. Graft materials past and future George Hamilton; 29. Graft infections M. Vicaretti and J. Fletcher.

Reviews

"This comprehensive, evidence-based account of the current mechanisms and pathogenesis of many common clinical entities resulting in vascular diseases details the established and novel interventions available to treat these conditions. A worldwide group of expert contributors, under the editorship of two eminent vascular surgeons, Robert Fitridge and Matthew Thompson, create a detailed, well-written, informative book....Although targeted at vascular surgeons and vascular trainees, this book will be of interest to a wider group of clinicians managing patients with vascular disease, including interventional radiologists. This is a must for all vascular trainees and all clinicians involved in the management of and research into vascular disease....This is a comprehensive, up-to-date resource detailing the current hypotheses of vascular disease development and outlining strategies to clinically manage the most common vascular conditions." --Doody's Review Service

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