Mapping Humanity
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Table of Contents

Contents

Introduction
Part I: The Human Genome 101
Chapter 1: The Basics of DNA, Chromosomes, and Genes
Chapter 2: Gene Mutations and Polymorphisms
Part II: DNA Sequencing Methods
Chapter 3: Sequencing DNA
Chapter 4: Next-Generation Sequencing
Chapter 5: Big Data!
Part III: Applications for Genomic Information
Chapter 6: Ancestry
Chapter 7: Neanderthal DNA
Chapter 8: Genetic Screening
Chapter 9: Genomic Justice
Chapter 10: Classical Methods to Search for Disease-Causing Mutations
Chapter 11: Genome-Wide Association Studies
Chapter 12: Twenty-First Century Eugenics?
Chapter 13: DNA and Prenatal Genetic Testing
Chapter 14: Pharmacogenomics
Chapter 15: Personalized Medicine
Chapter 16: Gene Therapy
Part IV: Genetic Engineering
Chapter 17: CRISPR-Clustered Regularly Interspaced Short Palindromic Repeats
Chapter 18: CRISPR Babies?
Chapter 19: GMOs-Genetically Modified Organisms
Chapter 20: The Future of Food?
Chapter 21: Pets-Ancestry, Health, and Cloning
Chapter 22: Conservation and Eradication
Part V: Beyond the Genome
Chapter 23: The Basics of Epigenetics
Chapter 24: Epigenetics in Action
Chapter 25: Mitochondrial DNA
Chapter 26: The Future

References
Index
Acknowledgments
About the Author

About the Author

Dr. Joshua Z. Rappoport received a bachelor's degree in Biology from Brown University and then went on to earn a PhD from the Program in Mechanisms of Disease and Therapeutics at the Mount Sinai School of Medicine Graduate School of Biological Sciences of New York University. Following defense of his thesis Dr. Rappoport went on to perform postdoctoral work at The Rockefeller University in New York City in the Laboratory of Cellular Biophysics. Subsequently he was recruited as a faculty member in the School of Biosciences at the University of Birmingham in England.

In 2014, Dr. Rappoport returned to the United States to become the Director of the Center for Advanced Microscopy and Nikon Imaging Center at the Northwestern University Feinberg School of Medicine, and a faculty member in the Department of Molecular and Cell Biology. Starting in March 2019, Dr. Rappoport took on the role of Executive Director of Research Infrastructure at Boston College, where he is now working to assist with strategic organization and operations in the core facility program at BC. Dr. Rappoport lives in Somerville, Massachusetts, with his wife Ema, a neuroscientist, and their dog Kris.

Reviews

"In Mapping Humanity, Joshua takes readers on a journey through the fascinating field of genetics. This book weaves together key scientific background information, exciting real-world applications, and important ethical issues in an accessible and engaging way."

-Marie McNeely, PhD, cofounder of People Behind the Science and Unfold Productions

"This book will serve as a very current and approachable way for the public to better understand this very interesting time in genetics and genomics, where the combination of sequencing and DNA manipulation technologies has brought us, while revealing the ethical and societal impacts."

-Elaine Mardis, coexecutive director of the Institute for Genomic Medicine at Nationwide Children's Hospital

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