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Management of Acute Coronary Syndromes

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Table of Contents

Part I. Pathophysiology The Spectrum of Myocardial Ischemia: The Paradigm of Acute Coronary Syndromes Christopher P. Cannon and Eugene Braunwald Linking Biochemistry, Vascular Biology, and Clinical Events in Acute Coronary Syndromes Richard C. Becker and Annemarie Armani Triggers of Acute Coronary Syndromes Peter M. Sapin and James E. Muller Insights into the Pathophysiology of Acute Ischemia Syndromes Using the TIMI Flow Grade, TIMI Frame Count, and TIMI Myocardial Perfusion Grade C. Michael Gibson, Sabina A. Murphy, and Jeffrey J. Popma Part II. Diagnosis Emergency Department Presentations of Acute Cardiac Ischemia J. Hector Pope and Harry P. Selker Early Identification and Treatment of Patients with Acute Coronary Syndromes Mary M. Hand and Costas T. Lambrew Serum Markers for Diagnosis and Risk Stratification in Acute Coronary Syndromes L. Kristin Newby, W. Brian Gibler, Robert H. Christenson, and E. Magnus Ohman Technologies to Diagnose Acute Ischemia Robert J. Zalenski, Joseph Lau, and Harry P. Selker Part III. ST-Segment Elevation Myocardial Infarction Thrombolytic Therapy Jeffrey L. Anderson and James S. Zebrack Primary Angioplasty Sorin J. Brener and Eric J. Topol Expanding the Access to Percutaneous Coronary Intervention for Patients Admitted to Community Hospitals Thomas P. Wharton, Jr. and Nancy Sinclair McNamara Antiplatelet and Anticoagulant Therapy Marc S. Sabatine and Ik-Kyung Jang b-Adrenergic Blockers, Calcium Channel Blockers, and Nitrates Yerem Yeghiazarians and Peter H. Stone Angiotensin Converting Enzyme Inhibitors After and During Acute Coronary Syndromes, and, in Particular, Myocardial Infarction Rodolfo Carrillo-Jimenez, Charles H. Hennekens, and Gervasio A. Lamas Risk Stratification: Exercise Testing, Imaging, and Cardiac Catheterization Sanjeev Puri, Hani A. Razek, and Bernard R. Chaitman Part IV. Non-ST-Segment Elevation Myocardial Infarction Anticoagulant Therapies, Marc Cohen. Antiplatelet Therapy Ian Conde-Pozzi and Neal S. Kleiman Thrombolytics and Invasive vs Conservative Strategies in Unstable Angina Ali Moustapha and H. Vernon Anderson Current Device Strategies in the Management of Acute Coronary Syndromes Kanwar P. Singh and C. Michael Gibson Part V. Special Aspects of Acute Coronary Syndromes Women and Acute Coronary Syndromes Jane A. Leopold and Alice K. Jacobs The Modern Strategy for Cardiogenic Shock Gary E. Lane and David R. Holmes, Jr. Myocardial Infarction in the Younger Patient James C. Fang and Jorge Plutzky Cholesterol Lowering Terje R. Pedersen and Serena Tonstad 'Secondary Prevention' of Myocardial Infarction Jorge Plutzky and Roger S. Blumenthal Cost and Cost-Effectiveness in Acute Coronary Syndromes William S. Weintraub Smoking Cessation Beth C. Bock and Bruce Becker Critical Pathways for Acute Coronary Syndromes Christopher P. Cannon and Patrick T. O'Gara Index


Reviews of the first edition: Foreword by Eugene Braunwald, MD "The review of the data on the diagnostic and prognostic utility of serum markers of cardiac injury is especially thorough. The treatments of thrombolytic therapy and primary angioplasty for acute myocardial infarction are complete, timely, and objective...[the] section on special aspects of acute coronary syndromes summarizes well the important issues of gender bias (or lack thereof) in cardiovascular medicine and the impact of lowering cholesterol." -Annals of Internal Medicine "This is an excellent and concise review of the spectrum of unstable angina, ST segment elevation infarction, and ST segment depression infarction. . .It spends a good deal of time on explaining the serum markers for myocardial ischemia as well as their pathophysiologic differences between ST elevation and ST depression infarction and the rationale for specific treatment strategies. Data on primary angioplasty and the thrombolytic trials are reviewed in detail. . .The numerous tables and charts are well designed and emphasize important topics covered in the text. . .This book is an excellent summary of acute coronary syndromes. It is well thought out and easy to read, which allows the reader to assimilate a lot of information in a short period of time. Its clear writing and effective use of tables and graphics solidifies understanding this essential topic in cardiology."-5 stars, Doody's Health Sciences Book Review Journal "... an outstanding compendium of what is currently known about the etiology, diagnosis, and treatment of acute coronary syndromes....The chapter references are extensive and up-to-date. The illustration, tables and charts are well done and easily interpreted....In summary, this is an outstanding work that should be on the reading list of everyone who deals with cardiac care. Emergency physicians and cardiologists should read it from cover to cover and there is something for everyone here." -The Journal of Emergency Medicine "...a valuable resource for cardiologists and emergency physicians...will also serve residents, fellows, internists, and practicing physicians." -Circulation "...contains a large amount of useful information..." -Journal of Family Practice "...should be on the reading list of everyone who deals with cardiac care..." -Journal of Emergency Medicine " excellent summary of acute coronary syndromes...allows the reader to assimilate a lot of information in a short period of time." -Doody's Health Sciences Book Review Journal

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