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Harrison's Manual of Medicine
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Table of Contents

Contributors
Preface
Acknowledgments
SECTION 1: CARE OF THE HOSPITALIZED PATIENT
1. Initial Evaluation and Admission Orders for the General Medicine Patient
2. Electrolytes/Acid-Base Balance
3. Diagnostic Imaging in Internal Medicine
4. Procedures Commonly Performed by Internists
5. Principles of Critical Care Medicine
6. Pain and its Management
7. Assessment of Nutritional Status
8. Enteral and Parenteral Nutrition
9. Transfusion and Pheresis Therapy
10. Palliative and End-of-Life Care
SECTION 2: MEDICAL EMERGENCIES
11. Cardiovascular Collapse and Sudden Death
12. Shock
13. Sepsis and Septic Shock
14. Acute Pulmonary Edema
15. Acute Respiratory Distress Syndrome
16. Respiratory Failure
17. Confusion, Stupor, and Coma
18. Stroke
19. Subarachnoid Hemorrhage
20. Increased Intracranial Pressure and Head Trauma
21. Spinal Cord Compression
22. Hypoxic-Ischemic Encephalopathy
23. Status Epilepticus
24. Diabetic Ketoacidosis and Hyperosmolar Coma
25. Hypoglycemia
26. Infectious Disease Emergencies
27. Oncologic Emergencies
28. Anaphylaxis
29. Bites, Venoms, Stings, and Marine Poisonings
30. Hypothermia and Frostbite
31. Poisoning and Drug Overdose
32. Bioterrorism
SECTION 3: COMMON PATIENT PRESENTATIONS
33. Chest Pain
34. Abdominal Pain
35. Headache
36. Back and Neck Pain
37. Fever, Hyperthermia, Chills, and Rash
38. Pain and Swelling of Joints
39. Syncope
40. Dizziness and Vertigo
41. Acute Visual Loss and Double Vision
42. Weakness and Paralysis
43. Tremor and Movement Disorders
44. Aphasias and Related Disorders
45. Sleep Disorders
46. Dyspnea
47. Cough and Hemoptysis
48. Cyanosis
49. Edema
50. Nausea, Vomiting, and Indigestion
51. Weight Loss
52. Dysphagia
53. Diarrhea, Constipation, and Malabsorption
54. Gastrointestinal Bleeding
55. Jaundice and Evaluation of Liver Function
56. Ascites
57. Azotemia and Urinary Abnormalities
58. Anemia and Polycythemia
59. Lymphadenopathy and Splenomegaly
60. Generalized Fatigue
SECTION 4: OPHTHALMOLOGY AND OTOLARYNGOLOGY
61. Common Disorders of Vision and Hearing
62. Sinusitis, Pharyngitis, Otitis, and Other Upper Respiratory Infections
SECTION 5: DERMATOLOGY
63. General Examination of the Skin
64. Common Skin Conditions
SECTION 6: HEMATOLOGY AND ONCOLOGY
65. Examination of Blood Smears and Bone Marrow
66. Red Blood Cell Disorders
67. Leukocytosis and Leukopenia
68. Bleeding and Thrombotic Disorders
69. Cancer Chemotherapy
70. Myeloid Leukemias, Myelodysplasia, and Myeloproliferative Syndromes
71. Lymphoid Malignancies
72. Skin Cancer
73. Head and Neck Cancer
74. Lung Cancer
75. Breast Cancer
76. Tumors of the Gastrointestinal Tract
77. Genitourinary Tract Cancer
78. Gynecologic Cancer
79. Prostate Hyperplasia and Carcinoma
80. Cancer of Unknown Primary Site
81. Paraneoplastic Endocrine Syndromes
82. Neurologic Paraneoplastic Syndromes
SECTION 7: INFECTIOUS DISEASES
83. Diagnosis of Infectious Diseases
84. Antibacterial Therapy
85. Health Care-Associated Infections
86. Infections in the Immunocompromised Host
87. Infective Endocarditis
88. Intraabdominal Infections
89. Infectious Diarrheas
90. Sexually Transmitted Diseases and Reproductive Tract Infections
91. Infections of the Skin, Soft Tissues, Joints, and Bones
92. Pneumococcal Infections
93. Staphylococcal Infections
94. Streptoccal/Enterococcal Infections, Diphtheria, and Other Infections Caused by Corynebacteria and Related Species
95. Meningococcal and Listerial Infections
96. Infections Caused by Haemophilus, Bordetella, Moraxella, and HACEK Group Organisms
97. Diseases Caused by Gram-Negative Enteric Bacteria, Pseudomonas, and Legionella
98. Infections Caused by Miscellaneous Gram-Negative Bacilli 99. Anaerobic Infections
100. Nocardiosis and Actinomycosis
101. Tuberculosis and Other Mycobacterial Infections
102. Lyme Disease and Other Nonsyphilitic Spirochetal Infections
103. Rickettsial Diseases
104. Mycoplasma Infections
105. Chlamydial Infections
106. Herpesvirus Infections
107. Cytomegalovirus and Epstein-Barr Virus Infections
108. Influenza and Other Viral Respiratory Diseases
109. Rubeola, Rubella, Mumps, and Parvovirus Infections
110. Enteroviral Infections
111. Insect- and Animal-Borne Viral Infections
112. HIV Infection and AIDS
113. Fungal Infections
114. Pneumocystis Infections
115. Protozoal Infections
116. Helminthic Infections and Ectoparasite Infestations
SECTION 8: CARDIOLOGY
117. Physical Examination of the Heart
118. Electrocardiography
119. Noninvasive Examination of the Heart
120. Congenital Heart Disease in the Adult
121. Valvular Heart Disease
122. Cardiomyopathies and Myocarditis
123. Pericardial Disease
124. Hypertension
125. Metabolic Syndrome
126. ST-Segment Elevation Myocardial Infarction (STEMI)
127. Unstable Angina and Non-ST-Elevation Myocardial Infarction
128. Chronic Stable Angina
129. Bradyarrhythmias
130. Tachyarrhythmias
131. Congestive Heart Failure and Cor Pulmonale
132. Diseases of the Aorta
133. Peripheral Vascular Disease
134. Pulmonary Hypertension
SECTION 9: PULMONARY
135. Respiratory Function and Pulmonary Diagnostic Procedures
136. Asthma
137. Environmental Lung Diseases
138. Chronic Obstructive Pulmonary Disease
139. Pneumonia and Lung Abscess
140. Pulmonary Thromboembolism and Deep-Vein Thrombosis
141. Interstitial Lung Disease
142. Diseases of the Pleura and Mediastinum
143. Disorders of Ventilation
144. Sleep Apnea
SECTION 10: NEPHROLOGY
145. Approach to the Patient with Renal Disease
146. Acute Renal Failure
147. Chronic Kidney Disease and Uremia
148. Dialysis
149. Renal Transplantation
150. Glomerular Diseases
151. Renal Tubular Disease
152. Urinary Tract Infections
153. Renovascular Disease
154. Nephrolithiasis
155. Urinary Tract Obstruction
SECTION 11: GASTROENTEROLOGY
156. Peptic Ulcer and Related Disorders
157. Inflammatory Bowel Diseases
158. Colonic and Anorectal Diseases
159. Cholelithiasis, Cholecystitis, and Cholangitis
160. Pancreatitis
161. Acute Hepatitis
162. Chronic Hepatitis
163. Cirrhosis and Alcoholic Liver Disease
164. Portal Hypertension
SECTION 12: ALLERGY, CLINICAL IMMUNOLOGY, AND RHEUMATOLOGY
165. Diseases of the Immediate Type Hypersensitivity
166. Primary Immune Deficiency Diseases
167. SLE, RA, and Other Connective Tissue Diseases
168. Vasculitis
169. Ankylosing Spondylitis
170. Psoriatic Arthritis
171. Reactive Arthritis
172. Osteoarthritis
173. Gout, Pseudogout, and Related Diseases
174. Other Musculoskeletal Disorders
175. Sarcoidosis
176. Amyloidosis
SECTION 13: ENDOCRINOLOGY AND METABOLISM
177. Disorders of the Anterior Pituitary and Hypothalamus
178. Diabetes Insipidus and SIADH
179. Thyroid Gland Disorders
180. Adrenal Gland Disorders
181. Obesity
182. Diabetes Mellitus
183. Disorders of the Male Reproductive System
184. Disorders of the Female Reproductive System
185. Hypercalcemia and Hypocalcemia
186. Osteoporosis and Osteomalacia
187. Hypercholesterolemia and Hypertriglyceridemia
188. Hemochromatosis, Porphyrias, and Wilson's Disease
SECTION 14: NEUROLOGY
189. The Neurologic Examination
190. Neuroimaging
191. Seizures and Epilepsy
192. Alzheimer's Disease and Other Dementias
193. Parkinson's Disease
194. Ataxic Disorders
195. ALS and Other Motor Neuron Diseases
196. Autonomic Nervous System Disorders
197. Trigeminal Neuralgia, Bell's Palsy, and Other Cranial Nerve Disorders
198. Spinal Cord Diseases
199. Tumors of the Nervous System
200. Multiple Sclerosis (MS)
201. Acute Meningitis and Encephalitis
202. Chronic Meningitis
203. Peripheral Neuropathies, Including Guillain-Barre Syndrome (GBS)
204. Myasthenia Gravis (MG)
205. Muscle Diseases
SECTION 15: PSYCHIATRY AND SUBSTANCE ABUSE
206. Psychiatric Disorders
207. Psychiatric Medications
208. Eating Disorders
209. Alcoholism
210. Narcotic Abuse
SECTION 16: DISEASE PREVENTION AND HEALTH MAINTENANCE
211. Routine Disease Screening
212. Immunization and Advice to Travelers
213. Cardiovascular Disease Prevention
214. Prevention and Early Detection of Cancer
215. Smoking Cessation
216. Women's Health
SECTION 17: ADVERSE DRUG REACTIONS
217. Adverse Drug Reactions
SECTION 18: LABORATORY VALUES
218. Laboratory Values of Clinical Importance
Index

About the Author

Dennis L. Kasper, MD, MA (Hon)William Ellery Channing Professor of MedicineProfessor of Microbiology and Molecular GeneticsExecutive Dean for Academic ProgramsHarvard Medical SchoolDirector, Channing LaboratoryDepartment of MedicineBrigham and Women's Hospital Among his many accomplishments, Dr. Braunwald is the editor of HEART DISEASE; a major competitor to HURST'S THE HEART and he is one of the primary editors of Harrison's PRINCIPLES OF INTERNAL MEDICINE. Anthony S. Fauci, MDChief, Laboratory of ImmunoregulationDirector, National Institute of Allergy and Infectious DiseasesNational Institutes of Health. In 2008, Dr. Fauci was awarded the Presidential Medal of Freedom, the Nation's highest civil award. Stephen L. Hauser, MDChairman and Betty Anker Fife ProfessorDepartment of NeurologyUniversity of California, San Francisco Dan L. Longo, MDScientific DirectorNational Institute on AgingNational Institutes of HealthBethesda, Maryland C.F. Kettering Professor of Medicine, Chief, Division of Endocrinology, Metabolism and Molecular Medicine Northwestern University Medical School, Chicago, IL.

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