The Handbook of Clinically Tested Herbal Remedies, Volumes 1 & 2


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Table of Contents


  • About the Editor
  • Contributors
  • Preface
  • Acknowledgments
  • Editor's Note
  • Chapter 1. History and Regulation of Botanicals in the United States (Loren D. Israelsen and Marilyn Barrett)
  • Introduction
  • History
  • DSHEA Explained
  • Drugs: OTC and Rx
  • Prospectus
  • Chapter 2. Product Definition Deficiencies in Clinical Studies of Herbal Medicines (Varro E. Tyler)
  • Chapter 3. Identifying and Characterizing Botanical Products (Marilyn Barrett)
  • Identifying Plants by Name
  • Means of Assuring Plant Identity
  • Preparations and Formulations
  • Dose
  • Bioavailability
  • Guidelines
  • Appendix: Preparations and Formulations
  • Chapter 4. Standardization of Botanical Preparations: What It Does and Does Not Tell Us (Uwe Koetter and Marilyn Barrett)
  • Introduction
  • Standardization of Therapeutic Activity
  • Standardization to Meet a Chemical Norm
  • Standardization As a Reflection of Quality Assurance Programs
  • Guidance
  • Situation in the Marketplace
  • Perspective
  • Chapter 5. The Importance and Difficulty in Determining the Bioavailability of Herbal Preparations (Anton Biber and Friedrich Lang)
  • Chapter 6. "Borrowed Science" and "Phytoequivalence": Can Two Herbal Products Be Judged Equivalent? (Marilyn Barrett)
  • Chemical or Pharmaceutical Equivalency
  • Bioequivalency or Therapeutic Equivalency
  • Application of the Concepts, Ginkgo As an Example
  • Meta-Analyses
  • Perspective
  • Chapter 7. Determining Efficacy of Herbal Preparations (Tieraona Low Dog)
  • Observational Medicine
  • "Evidence-Based" Medicine
  • Summary
  • Chapter 8. Evaluating Safety of Herbal Preparations (Ezra Bejar, Joseph M. Betz, and Marilyn Barrett)
  • Evaluation of Safety
  • Adverse Reactions
  • Adverse-Event Reporting Systems
  • Categorization According to the Degree of Safety
  • Product Quality As an Aspect of Safety
  • Contraindications
  • Drug-Herb Interactions
  • Improving Our Knowledge of Safety
  • Chapter 9. Conducting Clinical Trials on Herbal Dietary Supplements in North America: Commercialization, Confidence, and Conflicts (Anthony L. Almada)
  • The Spirit to Sponsor: Is There an Adequate Economic Incentive to Fund Research?
  • Extracting Value from Science
  • Competitor Kevlar: Preventing Piracy of Product-Specific Data
  • How Much Data Is Enough?
  • We Have Data Now What?
  • Who Has Science and How Did They Acquire It?
  • Conclusion
  • Chapter 10. Motives for Conducting Clinical Trials on Botanicals in Europe: A Focus on Germany (Joerg Gruenwald and Stefan Spiess)
  • Chapter 11. Pharmacopoeias and Botanical Monographs (Marilyn Barrett, Roy Upton, and V. Srini Srinivasan)
  • United States Pharmacopeia and National Formulary (USP-NF)
  • American Herbal Pharmacopoeia (AHP) and Therapeutic Compendium
  • European Pharmacopoeia (EP)
  • British Herbal Pharmacopoeia (BHP) and British Herbal Compendium (BHC)
  • German Commission E
  • European Scientific Cooperative of Phytotherapy (ESCOP)
  • Chinese Pharmacopoeia
  • African Pharmacopoeia
  • The Pharmacopoeia of Japan
  • The Pharmacopoeias of India
  • World Health Organization (WHO)
  • Other Pharmacopoeias
  • Summary and Perspective
  • Sources of Pharmacopoeias
  • Chapter 12. Methods of Product and Trial Inclusion and Evaluation (Marilyn Barrett)
  • Gathering Information on Products and Trials

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