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The Frontal Lobes and Neuropsychiatric Illness
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An examination of the frontal lobes and their relationship to neuropsychiatric illness. The volume brings together the work of 26 experts in clinical neuropsychiatry, neuropsychology, neuroscience and neuroimaging. Part One introduces frontal lobe dysfunction, arguing that our ageing population, with its decline in executive cognitive abilities, mandates corresponding eligibility and treatment changes in public and private health disability policies. Part Two delineates the anatomy and neurochemistry of the extended frontal systems underlying neuropsychiatric illnesses such as obsessive-compulsive disorder (OCD) and schizophrenia, details the role of the prefrontal cortex in consciousness and self-awareness, and offers a tantalizing theory on the lateralization of prefrontal cognitive functions. Part Three focuses on clinical practice, diagnosis and treatment strategies. Part Four covers the role of the frontal lobes in major neuropsychiatric illness such as depression and schizophrenia, describes the neurological substrates of content-specific delusions, and concludes with a report on the stereotactic neurosurgical treatment of refractory OCD.
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Table of Contents

ContributorsPART 1: IntroductionChapter 1. The Frontal Lobes and Neuropsychiatric IllnessChapter 2. The Significance of Frontal System Disorders for Medical Practice and Health PolicyPART 2: Functional Organization of Prefrontal Lobe SystemsChapter 3. Frontal Subcortical Circuits: Anatomy and FunctionChapter 4. The Orbitofrontal CortexChapter 5. Working Memory Dysfunction in SchizophreniaChapter 6. Lateralization of Frontal Lobe FunctionsChapter 7. Consciousness, Self-Awareness, and the Frontal LobesPART 3: Prefrontal Syndromes in Clinical PracticeChapter 8. Regional Prefrontal Syndromes: A Theoretical and Clinical OverviewChapter 9. Assessment of Frontal Lobe FunctionsChapter 10. Diagnosis and Treatment of "Frontal Lobe" SyndromesChapter 11. Treatment Strategies for Patients With Dysexecutive SyndromesPART 4: Frontal Lobe Dysfunction in Neuropsychiatric DisordersChapter 12. Frontal Lobe Dysfunction in Secondary DepressionChapter 13. The Frontal Lobes and SchizophreniaChapter 14. The Frontal Lobes and Traumatic Brain InjuryChapter 15. The Frontal Lobes and Content-Specific DelusionsChapter 16. Neurosurgical Treatment for Refractory Obsessive-Compulsive Disorder: Implications for Understanding Frontal Lobe FunctionIndex

About the Author

Stephen P. Salloway, M.D., M.S., is Associate Professor of Neurosciences and Psychiatry and Human Behavior at Brown University School of Medicine, and Director of Neurology and the Memory Disorders Program at Butler Hospital in Providence, Rhode Island. Paul F. Malloy, Ph.D., is Associate Professor of Psychiatry and Human Behavior at Brown University, and Director of Psychology at Butler Hospital in Providence, Rhode Island. James D. Duffy, M.B., Ch.B., is Medical Director of the Huntington�s Disease Program at the University of Connecticut Health Center; Associate Professor of Psychiatry at the University of Connecticut School of Medicine in Farmington, Connecticut; and Director of Psychiatric Consultation Services at Hartford Hospital in Hartford, Connecticut.

Reviews

"This book makes recent advances in the understanding of frontal function available to students, clinicians, and researchers who might not otherwise have experience in cognitive neuroscience. Frontal dysfunction is directly related to disability in neuropsychiatric disorders. Understanding how to help our patients begins with understanding the causes of their disability. This volume provides an excellent start."-- "Sheldon Benjamin, M.D., Journal of Clinical Psychiatry", "July 2002"

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