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Evolutionary Parasitology
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Parasites are everywhere, affecting almost every aspect imaginable in the life of their hosts including physiology, behaviour, life histories and, by implication, the structure of entire ecosystems. To cope with these constant threats, host immune defences have evolved to become one of the most sophisticated natural systems known. Despite this, parasites have found their own ways to overcome defences and exploit their hosts. Consequently, hosts and parasites have been constantly forced to adapt to one another; sometimes changes have occurred very rapidly, whilst others have taken eons. This evolutionary arms race has had far-reaching consequences for the biology of both parties. Over the last decade, principles from evolution and ecology have increasingly been applied to the fields of parasitology and immunology in an attempt to foster a common conceptual framework that uses a priori principles to unravel the diversity of host-parasite phenomena. This has led to the emergence of some of the most important, highly successful and inter-disciplinary areas of modern biology - the as yet separated fields of ecological immunology and evolutionary studies of parasitism. This novel book provides the first comprehensive overview of the many facets of host-parasite interactions, from the molecular bases to adaptive strategies and their ecological and evolutionary consequences. It is informed by the very latest progress in the field. No longer do we view well-adapted parasites as becoming ultimately harmless. To the contrary, parasite virulence is determined both by the processes that lead to harm and by the evolutionary costs and benefits of this damage. Similarly, parasitism is no longer regarded as being inevitably deleterious; rather it can be a major factor maintaining diversity in populations and communities, selecting for beautiful plumages of birds, or even making us more social. Evolutionary Parasitology integrates material from a wide range of topics including immunology, genetics, sexual selection, population ecology, behavioural ecology, and evolutionary biology. Graduate students and researchers from different fields and with different backgrounds will find this book a valuable reference to meet their interests and to expand their insights into neighbouring disciplines.
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Table of Contents

Foreword ; 1. Parasites and Humans ; 2. The Study of Evolutionary Parasitology ; 3. The Diversity and Natural History of Parasites ; 4. The Natural History of Defences ; 5. Ecological Immunology ; 6. Parasites, Immunity, and Sexual Selection ; 7. Specificity ; 8. Parasite Immune Evasion and Manipulation of Host Phenotype ; 9. Infection and Pathogenesis ; 10. Host-Parasite Genetics ; 11. Epidemiology ; 12. Virulence ; 13. Host-Parasite (Co-)Evolution ; 14. Parasites and Host Ecology ; Glossary ; Immunological Acronyms ; References ; Index

About the Author

Paul Schmid-Hempel studied biology at the University of Zurich and in 1982 he received his PhD on the ecology of the Sahara Desert ant. He went on to do post-doctoral work at Oxford University (1982-1984) where he worked on an analysis of optimal strategies of animals. He then moved to the Zoological Institute of the University of Basel, where he was part of that group which set a new course for evolutionary ecology. In 1991 he was appointed professor for experimental ecology at the ETH Zurich, and is now Director of the Genetic Diversity Centre there. Since 2008 he has also been a non-resident Permanent Fellow of the Wissenschaftskolleg zu Berlin. His current research focuses on host-parasite interactions and co-evolution, maintenance of genetic diversity, recombination, social systems, immune defence strategies, and ecological immunology. He has published around 180 original articles, two books, and many articles in newspapers as part of his work in the public understanding of science.

Reviews

... a wonderful and updated introduction to parasitology, full of fascinating examples and thought-provoking ideas. I think any current researcher in parasitology, or anyone with a slight interest in the field, would undoubtedly benefit from reading at least some of the various topics presented in this book. * Alejandra G. Jaramillo, TREE *

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