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Table of Contents

Chapter 1. Introduction to the Study of Epigenetics Chapter 2. The Basis of the Transcription Process Chapter 3. DNA Packaging and Chromatin Architecture Chapter 4. Modifying the Structure of Chromatin Chapter 5. DNA Methylation Chapter 6. Post-Translational Modification of Histones Chapter 7. Histone Modification Machinery Chapter 8. Locus-Specific Control of Histone-Modifying Enzyme Action Chapter 9. Epigenetic Control of Cell-Specific Gene Expression Chapter 10. Epigenetic Control of the Mitotic Cell Cycle Chapter 11. The Epigenetic Basis of Gene Imprinting Chapter 12. Epigenetic Control of Cellular Differentiation Chapter 13. Reversibility of Epigenetic Modification Patterns Chapter 14. Epigenetic Predisposition to Disease and Imprinting-Based Disorders Chapter 15. Epigenetics of Memory, Neurodegeneration, and Mental Health Chapter 16. Epigenetics of Cancer


"Armstrong's Epigenetics textbook is not only timely but also important for introducing scientists, new and seasoned, to the ever-evolving world of epigenetics." - The Quarterly Review of Biology, 2016, Vol. 91, No. 2 "The author has made a very thorough presentation of several areas within the field of epigenetics. The material has been presented in a comprehensive, well-organized and understandable manner. He allows the reader to gain a strong foundation of each subject area by including detailed introductory sections. The coverage of the topics will allow the reader to obtain both general knowledge and also more detailed understanding of the regulating mechanisms involved in epigenetic changes and the consequences of those changes.The content is also relevant to current trends in the field of epigenetics and includes reviews of disease states related to epigenetics, such as cancer, which are actively being researched." - WhatIsEpigenetics "In summary, Epigenetics provides a convincing overview of epigenetic mechanisms at the molecular and cellular levels. Clearly, such mechanisms are likely to be relevant to many complex human diseases, but the details remain to be elucidated. The enduring impression taken away from this book is of a spectacularly complex and dynamic interplay among different epigenetic factors in the regulation of gene expression and cellular differentiation. Any researcher interested in these phenomena should find this textbook an excellent resource." - International Journal of Epidemiology, 2015, Vol. 44, No. 4

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