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Diseases of the Liver and Biliary System in Children


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Table of Contents

Contributors, vii Foreword to the First Edition, x Preface, xi Acknowledgments, xii Section 1 Understanding the Liver 1 Structure, Function, and Repair of the Liver, 3 Christoph Leiskau and Ulrich Baumann 2 Liver Pathology in Children, 18 Rachel M. Brown 3 Liver Immunology and Its Application in Diseases, 24 Hannah C. Jeffery, Kathryn Stirling, and Ye Htun Oo 4 Molecular Genetics and Liver Disease, 34 Paul Gissen Section 2 Investigating the Liver 5 Useful Investigations in the Assessment of Liver Disease, 41 Way S. Lee and Deirdre A. Kelly Section 3 Supporting the Child and Family 6 Multidisciplinary Approach to Liver Disease, 59 6.1 The Role of the Multidisciplinary Team, 60 Lindsay Hogg 6.2 The Role of the Dietitian, 68 Sara Clarke and Kelly Guthrie 6.3 The Role of the Psychologist, 76 Jacqueline Blyth Section 4 Liver Disease in Pregnancy 7 The Effects of Liver Disease in Pregnancy on Mother and Child, 83 Jane Hartley and Hanns ]Ulrich Marschall Section 5 Liver Disease in Infancy 8 The Jaundiced Baby, 99 Jane Hartley 9 The Acutely Ill Baby, 127 Patrick J. McKiernan 10 Neonatal Hemochromatosis, 144 Amy G. Feldman, Estella M. Alonso, and Peter F. Whitington Section 6 Liver Disease in Older Children 11 Autoimmune Liver Disease, 155 Giorgina Mieli ]Vergani and Diego Vergani 12 Drug ]Induced Liver Disease, 169 Noelle H. Ebel and Karen F. Murray 13 Viral Hepatitis, 191 Mona Abdel ]Hady and C. Y. William Tong 14 Congenital and Structural Abnormalities of the Liver, 211 Larissa Kerecuk and Patrick J. McKiernan 15 Non ]Alcoholic Steatohepatitis in Childhood, 227 Claudia Della Corte, Antonella Mosca, Vincenzina Lucidi, Arianna Alterio, and Valerio Nobili 16 Hepatobiliary Disease in Cystic Fibrosis, 241 Carla Colombo and Dominique Debray Section 7 Acute Liver Disease 17 Non ]Viral Infectious Liver Disease, 259 Samantha M. Lissauer and Shiva Ramroop 18 Acute Liver Failure, 271 Estella M. Alonso and Robert H. Squires Section 8 Metabolic Liver Disease 19 Metabolic Liver Disease in the Infant and Older Child, 291 Anupam Chakrapani and Paul Gissen 20 Disorders of Copper Metabolism, 323 Thomas Muller and Stuart Tanner Section 9 Management of Chronic Liver Disease 21 Complications and Management of Chronic Liver Disease, 343 Noelle H. Ebel and Simon P. Horslen Section 10 The Liver and Other Organs 22 The Liver in Systemic Illness, 369 Sue V. Beath 23 Skin Disorders in Liver Disease, 389 Indra D. M. van Mourik, Malobi I. Ogboli, and Michelle Thomson 24 Dental Care of Children with Liver Disease, 405 Marie Therese Hosey and Victoria Clark Section 11 Surgical Disorders of the Liver and Bile Ducts 25 Biliary Atresia and Other Causes of Surgical Jaundice in Infancy, 415 Erica Makin and Mark Davenport 26 Liver Trauma in Children, 430 A. B. (Sebastian) van As and Alastair J. W. Millar 27 Surgical Management of Portal Hypertension, 439 Jean de Ville de Goyet 28 Primary Hepatic Tumors, 459 Bruce Morland and Khalid Sharif 29 Disorders of the Pancreas, 479 Heiko Witt, Narendra Battula, and Darius Mirza Section 12 Transplantation 30 Anesthesia and Intensive Care in Pediatric Liver Disease, 501 Peter Bromley, James Bennett, and Richard Neal 31 Liver Transplantation, 512 Deirdre A. Kelly and Paolo Muiesan 32 Small ]Bowel Transplantation in Children, 538 Girish L. Gupte and George Mazariegos 33 Combined Liver and Kidney Transplantation, 556 Thamara Perera and David V. Milford Section 13 Liver Disease Around the World 34 Liver Disease in the Developing World, 571 Vidyut Bhatia, Wafa'a Al ]Qabandi, Elizabeth Goddard, Seng Hock Quak, and Anupam Sibal Section 14 Pediatric Liver Disease in Adult Life 35 Transition to Adult Care, 595 Jo Wray and Jessica Wright 36 Pediatric Liver Disease: Surviving to Adult Life, 608 James Ferguson Index, 615

About the Author

Prof Deirdre Kelly is one of the world's leading pediatric hepatologists, and was responsible for helping create the Paediatric Liver Unit at Birmingham Children's Hospital, a leading national and international institution for children with liver disease and undergoing liver transplantation. She runs an active research programme focussing on viral hepatitis in children, molecular genetics of inherited liver disease, and quality/outcome of life following liver/intestinal transplantation. She's a former President of the European Society of Paediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN), the British Society for Paediatric Gastroenterology, Hepatology and Nutrition and the International Paediatric Transplant Association. She has been on the editorial boards of the Journal of Liver Transplantation and Surgery, Pediatric Transplantation and Alimentary Pharmacology & Therapeutics, and has had 250 papers published, as well as 7 books and 26 book chapters.

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