1: Introduction
2: Genetic Principles
3: Laboratory Organization
4: Specimens
5: DNA Amplification
6: Analysis Techniques
7: Probes, Allele Mutations, and Restriction Enzymes
8: Probability and Statistical Analysis
9: Quality Control
10: Legal and Ethical Considerations
11: Case Applications
Lorne T. Kirby is with the Department of pathology at the University of British Columbia.
"An interesting historical document that will also be of some use
to those with different perspectives. . . . a good introduction to
the basic technology of DNA fingerprinting. For anyone coming to
this technique without a strong lab background, the refresher
chapter on basic genetic principles is helpful, and the
step-by-step approach to major technical procedures is well
planned. . . . having this book is hand will save a novice weeks
that would otherwise be
spent thrashing through primary literature and textbooks to
accumulate both the latest techniques and fundamental principles."
--Trends in Ecology and Evolution
"The strength of this book rests with its extensive collection of
laboratory methodologies pertinent to DNA identification processes.
The coverage is comprehensive. . . . extremely readable."
--Choice
"An excellent introductory text on DNA fingerprinting covering
probes, PCR, hybridization, sample taking, costs, law, ethics,
analysis-statistics, guidelines and other techniques relevant to
forensics. 4 stars out of 5." --American Association of Forensic
Dentists
"Very useful for students and laboratory personnel." --BIOSIS
"An interesting historical document that will also be of some use
to those with different perspectives. . . . a good introduction to
the basic technology of DNA fingerprinting. For anyone coming to
this technique without a strong lab background, the refresher
chapter on basic genetic principles is helpful, and the
step-by-step approach to major technical procedures is well
planned. . . . having this book is hand will save a novice weeks
that would otherwise be
spent thrashing through primary literature and textbooks to
accumulate both the latest techniques and fundamental principles."
--Trends in Ecology and Evolution
"The strength of this book rests with its extensive collection of
laboratory methodologies pertinent to DNA identification processes.
The coverage is comprehensive. . . . extremely readable."
--Choice
"An excellent introductory text on DNA fingerprinting covering
probes, PCR, hybridization, sample taking, costs, law, ethics,
analysis-statistics, guidelines and other techniques relevant to
forensics. 4 stars out of 5." --American Association of Forensic
Dentists
"Very useful for students and laboratory personnel." --BIOSIS
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