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Complex Interventions in Health
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Table of Contents

Foreword Peter Craig 1. The Complex Interventions Framework David A Richards 2. Knowledge for Healthcare Practice Ingalill Rahm Hallberg 3. The Value of Mixed Methods for Researching Complex Interventions Gunilla Borglin 4. The Critical Importance of Patient and Public Involvement for Research into Complex Interventions David A Richards Part 1: Developing Complex Interventions Part 1 Introduction Gabriele Meyer and Sascha Koepke 5. Systematic Reviews of the Effects of Interventions Nicky Cullum and Jo Dumville 6. Advanced Approaches to Evidence Synthesis and its Application to Intervention Design Nicky Cullum and Jo Dumville 7. Exploring Complexity in Systematic Reviews of Complex Interventions Sascha Koepke, Jane Noyes, Jackie Chandler and Gabriele Meyer 8. The Synthesis of Qualitative Data Jo Rycroft-Malone 9. Building a Case for Mixed Method Reviews Karin Hannes 10. Development of Complex Interventions: Outcome Modelling Susanne Buhse and Ingrid Muhlhauser 11. Designing Interventions to Change Health-related Behaviour Charles Abraham, Sarah Denford, Jane Smith, Sarah Dean, Colin Greaves, Jenny Lloyd, Mark Tarrant, Mathew White and Katrina Wyatt 12. Modelling Process and Outcomes in Complex Interventions Walter Sermeus Part 2: Investigating the Feasibility and Undertaking Pilot Testing of Complex Interventions: An Introduction Part 2 Introduction David A Richards 13. Pilot Studies and Feasibility Studies for Complex Interventions: An Introduction Lora Giangregorio and Lehana Thabane 14. How to Use Feasibility and Pilot Trials to Test Alternative Methodologies and Methodological Procedures Prior to Full Scale Trials Rod Taylor, Obioha C Ukoumunne and Fiona C Warren 15. How to Use Feasibility Studies to Derive Parameter Estimates in Order to Power a Full Trial Obioha C Ukoumunne, Fiona C Warren, Rod S Taylor and Paul Ewings 16. Addressing Issues in Recruitment and Retention Using Feasibility and Pilot Trials Shaun Treweek 17. Testing the Waters: Piloting a Complex Intervention Nancy Feeley and Sylvie Cossette 18. Feasibility in Practice: Undertaking a Feasibility Study to Answer Procedural, Methodological and Clinical Questions Prior to a Full-scale Evaluation David A Richards Part 3: Evaluation of Complex Interventions Part 3 Introduction Ingalill Rahm Hallberg 19. Individually and Cluster Randomised Trials Sallie Lamb and Douglas Altman 20. Stepped Wedge, Natural Experiments and Interrupted Time Series Analysis Design Yan Hu 21. Non-standard and Preference Designs Louise von Essen 22. Single-subject Designs Lena Nilsson Wikmar and Karin Harms-Ringdahl 23. Process Evaluation of Complex Interventions: A Summary of Medical Research Council Guidance Graham Moore, Suzanne Audrey, Mary Barker, Lyndal Bond, Chris Bonell, Wendy Hardeman, Laurence Moore, Alicia O'Cathain, Tannaze Tinati, Daniel E. Wight and Janis Baird 24. Intervention Fidelity in Clinical Trials Henna Hasson 25. Qualitative Process Evaluation for Complex Interventions Salla Atkins, Willem Odendaal, Natalie Leon, Elizabeth Lutge and Simon Lewin 26. Economic Evaluations of Complex Interventions Katherine Payne and Alexander J Thompson Part 4: Implementation of Complex Interventions Part 4 Introduction Theo van Achterbeg 27. Implementation Issues: Towards a Systematic and Stepwise Approach Ted A Skolarus and Anne E Sales 28. Why do Barriers and Facilitators Matter? Elizabeth J Dogherty and Carole A Estabrooks 29. How to Arrive at an Implementation Plan Theo van Achterberg 30. Applying Normalization Process Theory to the Implementation of Complex Interventions Carl May 31. Action Research for the Implementation of Complex Interventions Brendan McCormack 32. Systems Modelling for Improving Healthcare Martin Pitt, Thomas Monks and Michael Allen 33. A Few Final Thoughts Ingalill Rahm Hallberg and David A Richards

About the Author

David A. Richards is Professor of Mental Health Services Research at the University of Exeter Medical School.ã For many years he has been at the forefront of national and international efforts to improve access to treatment for those suffering from high prevalence mental health problems such as depression. A nurse by professional background, he is a UK National Institute of Health Research Senior Investigator, President of the European Academy of Nursing Science and chair of the European Science Foundation REFLECTION Research Network Programme, an interdisciplinary European Faculty of researchers, equipped to design, plan and implement programmatic, mixed methods and complex interventions research. Like Ingalill, he has frequently challenged the research community to reduce waste in their work by refocussing their research activity towards clinically relevant programmes, driven by the uncertainties of clinical practice and the real concerns of the public, patients and clinicians. Ingalill Rahm Hallberg is Professor in Health Care Science at Lund University, Sweden. She has been the pro-dean of the Medical Faculty, the assistant vice-chancellor and pro vice-chancellor of Lund University. She is a nurse by professional background. Her research has been on aging, care and services for older people and living with severe diseases, an area in which she has been at the forefront nationally and internationally. Her frequent involvement in reviewing research proposals, research at universities and by research groups nationally and internationally inspired her to initiate a debate on how research was very often scattered, lacking coherent programmes and dominated by descriptive studies with no impact on health care. As the previous president of the European Academy of Nursing Science she was, together with David, a driving force to change the unwelcome preponderance of small-scale, descriptive projects.

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