Table of Contents

1 Global Burden of Cardiovascular Disease 2 Ethical Decisions in Cardiovascular Medicine 3 Clinical Decision Making in Cardiology 4 Measurement and Improvement of Quality of Care: Relevance to Cardiovascular Clinical Practice 5 Critical Evaluation of Clinical Trials 6 Personalized and Precision Cardiovascular Medicine 7 Principles of Cardiovascular Genetics 8 Drug Therapeutics and Personalized Medicine 9 Biomarkers and Their Use in Precision Medicine 10 The History and Physical Examination: An Evidence-Based Approach 11 Evaluation and Management of the Noncardiac Surgical Patient 12 Electrocardiography 13 Exercise Testing 14 Echocardiography Appropriate Use Criteria: Echocardiography 15 The Chest Radiograph in Cardiovascular Disease 16 Nuclear Cardiology 17 Cardiovascular Magnetic Resonance 18 Cardiac Computed Tomography Appropriate Use Criteria: Multimodality Imaging in Stable Ischemic Heart Disease and Heart Failure 19 Cardiac Catheterization 20 Coronary Angiography and Intracoronary Imaging 21 Approach to the Patient With Heart Failure 22 Mechanisms of Cardiac Contraction and Relaxation 23 Pathophysiology of Heart Failure 24 Diagnosis and Management of Acute Heart Failure Guidelines: The Hospitalized Patient With Heart Failure 25 Management of Patients With Heart Failure With Reduced Ejection Fraction Guidelines: Management of Heart Failure with a Reduced Ejection Fraction 26 Heart Failure with a Preserved Ejection Fraction Guidelines: Heart Failure with a Preserved Ejection Fraction 27 Devices for Monitoring and Managing Heart Failure Guidelines: Cardiac Resynchronization Therapy and Implantable Cardioverter- Defibrillators for Heart Failure with a Reduced Ejection Fraction 28 Surgical Management of Heart Failure 29 Mechanical Circulatory Support 30 Cardiovascular Regeneration and Repair 31 Management of Patients with Advanced Heart Failure 32 Approach to the Patient with Cardiac Arrhythmias 33 Genetics of Cardiac Arrhythmias 34 Mechanisms of Cardiac Arrhythmias 35 Diagnosis of Cardiac Arrhythmias Guidelines: Ambulatory Electrocardiographic and Electrophysiological Testing 36 General Therapy for Cardiac Arrhythmias 37 Supraventricular Arrhythmias 38 Atrial Fibrillation: Clinical Features, Mechanisms, and Management Guidelines: Atrial Fibrillation 39 Ventricular Arrhythmias 40 Bradycardia Arrhythmias 41 Pacemakers and Implantable Cardioverter-Defibrillators Guidelines: Cardiac Pacemakers and Cardioverter-Defibrillators 42 Cardiac Arrest and Sudden Cardiac Death 43 Hypotension and Syncope Guidelines 44 The Vascular Biology of Atherosclerosis 45 Risk Markers and the Primary Prevention of Cardiovascular Disease 46 Systemic Hypertension: Mechanisms and Diagnosis 47 Systemic Hypertension: Management Guidelines: Treatment of Hypertension 48 Lipid Disorders and Cardiovascular Disease Guidelines: Management of Lipids 49 Nutrition and Cardiometabolic Diseases 50 Obesity and Cardiometabolic Disease 51 Diabetes and the Cardiovascular System Guidelines: Diabetes and Heart Disease 52 Environmental Exposures and CVD 53 Exercise and Sports Cardiology 54 Comprehensive Cardiac Rehabilitation 55 Complementary Approaches to Heart Disease Management 56 Approach to the Patient with Chest Pain 57 Coronary Blood Flow and Myocardial Ischemia 58 ST-Elevation Myocardial Infarction: Pathology, Pathophysiology, and Clinical Features 59 ST-Elevation Myocardial Infarction: Management Guidelines: Management of Patients with ST-Elevation Myocardial Infarction 60 Non-ST Elevation Acute Coronary Syndromes Guidelines: Unstable Angina and Non-ST Elevation Myocardial Infarction 61 Stable Ischemic Heart Disease Guidelines: Stable Ischemic Heart Disease 62 Percutaneous Coronary Intervention Guidelines: Percutaneous Coronary Intervention 63 Diseases of the Aorta Guidelines: Diseases of the Aorta 64 Peripheral Arterial Diseases Guidelines: Peripheral Arterial Diseases 65 Prevention and Management of Ischemic Stroke 66 Treatment of Noncoronary Obstructive Vascular Disease 67 Approach to the Patient with VHD 68 Aortic Valve Disease 69 Mitral Valve Disease 70 Tricuspid, Pulmonic, and Multivalvular Disease 71 Prosthetic Heart Valve 72 Transcatheter Therapies for Valvular Heart Disease Guidelines 73 Cardiovascular Infections Guidelines 74 Rheumatic Fever 75 Congenital Heart Disease in the Adult and Pediatric Patient Guidelines 76 Catheter-Based Treatment of Congenital Heart Disease 77 The Dilated, Restrictive, and Infiltrative Cardiomyopathies 78 Hypertrophic Cardiomyopathy 79 Myocarditis 80 Drug and Toxin-Induced Cardiomyopathies 81 Cardio-oncology 82 Cardiovascular Abnormalities in HIV-Infected Individuals 83 Pericardial Diseases Traumatic Heart Disease 84 Pulmonary Embolism 85 Pulmonary Hypertension 86 Chronic Lung Disorders and Cardiovascular Disease 87 Sleep Disordered Breathing and Cardiovascular Disease 88 Cardiovascular Disease in the Elderly 89 Cardiovascular Disease in Women 90 Pregnancy and Heart Disease Guidelines: Pregnancy and Heart Disease 91 Heart Disease in Varied Populations 92 Endocrine Disorders and Cardiovascular Disease 93 Hemostasis, Thrombosis, Fibrinolysis, and Cardiovascular Disease 94 Rheumatic Diseases and the Cardiovascular System 95 Tumors Affecting the Cardiovascular System 96 Psychiatric and Behavioral Aspects of Cardiovascular Disease 97 Neurologic Disorders and Cardiovascular Disease 98 Interface Between Renal and Cardiovascular Diseases 99 Cardiovascular Manifestations of Autonomic Disorders

About the Author

Dr. Peter Libby is a cardiovascular medicine specialist at Brigham and Women's Hospital (BWH) and the Mallinckrodt Professor of Medicine at Harvard Medical School (HMS). Dr. Libby received his medical degree from the University of California, San Diego School of Medicine. He completed a residency in internal medicine and a fellowship in cardiovascular disease at Peter Bent Brigham Hospital (now BWH). He also completed a research fellowship in cellular physiology at HMS. Dr. Libby is board certified in internal medicine and cardiovascular disease. The author of over 370 peer-reviewed publications, Dr. Libby's clinical and research interests include vascular biology, atherosclerosis and preventative cardiology. The research laboratory that Dr. Libby directs studies the messengers created by the body that may produce arterial plaque and blockages, as well as normal and abnormal function of smooth muscle and endothelial cells. Boston Magazine named Dr. Libby a top cardiologist. His research has received funding from the American Heart Association and National Institutes of Health. Dr. Libby has received research recognitions on four continents including the highest basic research awards from the American Heart Association and American College of Cardiology, the Gold Medal of the European Society of Cardiology, and the Anitchkow award from the European Atherosclerosis Society.