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Biomarkers in Oncology

New or Used: 4 copies from $195.95
This integrated book covers the entire spectrum of cancer biomarkers in development and clinical use. Predictive and prognostic markers are explored in the context of colon cancer, breast cancer, lung cancer, prostate cancer, and GIST. International experts provide insight into toxicity markers and surrogate markers. Attention is also given to biomarker assay development, validation, and strategies. A powerful tool for determining decisions on therapy, selecting drug regimens, monitoring the efficacy of treatment, and performing individualized surveillance, biomarkers represent the forefront of cancer research and treatment. As these technologies become increasingly available for clinical use, this book will be an essential resource for oncologists and translational researchers.
Product Details

Table of Contents

Ch. 1: Predictive Markers in Colon Cancer Armin Gerger, Melissa J. LaBonte, and Heinz-Josef Lenz Ch. 2: Prognostic Markers in Breast Cancer Agustin A. Garcia, and Nazish Ahmad Ch. 3: Predictive Markers in Lung Cancer Stephen V. Liu, and Barbara J. Gitlitz Ch. 4: Prostate Cancer: Predictive Markers in Clinical Development Courtney K. Phillips, and Daniel P. Petrylak Ch. 5: Biomarkers in GIST Howard J. Lim, and Charles D. Blanke Ch. 6: Cytogenetic and Molecular Aberrations as Predictive Biomarkers in Acute Myeloid Leukemia Steffen Heeg, and Cornelius F. Waller Ch. 7: Prognostic Markers in Colon Cancer Janine M. Davies, and Howard L. McLeod Ch. 8: Markers in Lung Cancer Edwin Y. Lin, Ravin Rupani, and Barbara J. Gitlitz Ch. 9: Molecular Markers of Prostate Cancer Outcome David Ian Quinn, and Gregory P. Swanson Ch. 10: Prediction of Chemotherapy Toxicities Pierre Laurent-Puig, Thierry Lecomte, Marie-Anne Loriot, Valerie Boige, and Helene Blons Ch. 11: Surrogate Markers-The Role of Positron Emission Tomography Scanning Derek G. Power, and David H. Ilson Ch. 12: Circulating Tumor Cells as Biomarkers Amir Goldkorn, Tong Xu, and Stephen V. Liu Ch. 13: Focus on Personalized Molecular Based Medicine Lex HT Van der Ploeg, Bud Mishra, Casimir P. Eitner, Jon Burrows, Thomas Wray Tombler, Jr., Vladimir Poponin, Dan J. Knauer, Ilia Ichetovkin, Richard M. Pinnola, Gregory A. Endress, and Patrick Soon-Shiong Ch. 14: Clinical Validation of Biomarkers Sumithra J. Mandrekar, and Daniel Sargent Ch. 15: Regulatory Issues Maxwell T. Vergo, and Al B. Benson III Ch. 16: Biomarkers for Safety Assessment and Clinical Pharmacology Stan Louie, and Jared Russell Ch. 17: Biomarker Discovery Strategies: DNA, RNA and Protein Eduardo Vilar, and Josep Tabernero Ch. 18: Biomarkers For Go/No Go Decisions Ben Markman, and Josep Tabernero

About the Author

Heinz-Josef Lenz, MD, FACP, Division of Medical Oncology, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033


From the reviews: "The new book Biomarkers in Oncology ... has the ambition to provide the overview about identification, development and clinical relevance of biomarkers in solid tumors and hematological malignancies. ... the book represents a valuable source of ideas and inspiration for basic scientists and physician scientists in the innovative translational research in oncology, for those who decide to step forward on the way filling demands of oncological patients." (Jan Sedlak, Neoplasma, Issue 6, 2013)

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