Table of Contents

1 Nutrition of Bacteria.- I. Major and Minor Bioelements.- II. The Two Basic Mechanisms of ATP Synthesis.- III. Nutrients as Energy Sources.- IV. Growth Factor Requirements of Bacteria.- V. Summary.- 2 How Escherichia coil Synthesizes ATP during Aerobic Growth on Glucose.- I. Transport of D-Glucose into theE.coliCell.- II. Degradation of Glucose-6-Phosphate to Pyruvate via the Embden—Meyerhof—Parnas (EMP) Pathway.- III. Oxidative Decarboxylation of Pyruvate to Acetyl-Coenzyme A.- IV. Oxidation of Acetyl-CoA via the Tricarboxylic Acid Cycle.- V. The Formation of ATP in the Respiratory Chain.- VI. Summary.- 3 Biosynthesis ofEscherichia colsCells from Glucose.- I. Composition of E. coli Cells.- II. Assimilation of Ammonia.- III. Assimilatory Reduction of Sulfate.- IV. Biosynthesis of Amino Acids.- V. How Pentose Phosphates and NADPH are Formed.- VI. Ribonucleotides and Deoxyribonucleotides.- VII. Biosynthesis of Lipids.- VIII. Formation of Carbohydrates.- IX. Synthesis of Polymers.- X. The Requirement for an Anaplerotic Sequence.- XI. Summary.- 4 Aerobic Growth of Escherichia coli on Substrates Other Than Glucose.- I. Fructose and Lactose as Substrates.- II. Pentoses as Substrates.- III. Acetate, Pyruvate, and L-Malate as Substrates.- IV. Summary.- 5 Metabolic Diversity of Aerobic Heterotrophs.- I. The Different Mechanisms for the Uptake of Substrates.- II. The Entner-Doudoroff Pathway.- III. Sugar Degradation via the Pentose Phosphate Cycle.- IV. The Methylglyoxal Bypass.- V. Diversity in Energy Metabolism.- VI. Dissimilatory Reduction of Nitrate.- VII. Bacterial Bioluminescence.- VIII. Alternate Anaplerotic Sequences.- IX. Biosynthesis of Monomers and Polymers.- X. Summary.- 6 Catabolic Activities of Aerobic Heterotrophs.- I. Degradation of Polymers by Exoenzymes.- II. Growth with Amino Acids.- III. Growth with Organic Acids.- IV. Growth with Aliphatic Hydrocarbons.- V. Growth with Aromatic Compounds.- VI. Growth with C1Compounds.- VII. Incomplete Oxidations.- VIII.Plasmid-Encoded Catabolic Activities.- IX. Summary.- 7 Regulation of Bacterial Metabolism.- I. Regulation of Enzyme Synthesis by Induction and Repression.- II. Regulation of Enzyme Activity.- III. Summary.- 8 Bacterial Fermentations.- I. Alcohol Fermentation.- II. Lactate Fermentation.- III. Butyrate and Butanol-Acetone Fermentation.- IV. Mixed Acid and Butanediol Fermentation.- V. Propionate and Succinate Fermentation.- VI. Acetate Fermentation.- VII. Methane Fermentation.- VIII. Sulfide Fermentation (Desulfurication).- IX. The Anaerobic Food Chain.- X. Fermentation of Nitrogenous Compounds.- Xl. Summary.- 9 Chemolithotrophic and Phototrophic Metabolism.- I. Chemolithotrophic Metabolism.- II. Assimilation of CO2.- III. Phototrophic Metabolism.- IV. Summary.- 10 Fixation of Molecular Nitrogen.- I. Nitrogen-fixing Organisms.- II. Biochemistry of Nitrogen Fixation.- III. Regulation of Nitrogenase.- IV. Summary.- Further Reading.- Index of Organisms.

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