Presents up-to-date information on the role of autophagy in health and disease
I. General Applications Chapter 1. Introduction; M. A. Hayat II. Role of Autophagy in Cancer Chapter 2. Molecular Crosstalk between the Autophagy and Apoptotic Networks in Cancer; James Driscoll Chapter 3. Inhibition of ERBB Receptors and Autophagy in Cancer Therapy; Ronit Pinkas-Kramarski Chapter 4. Ginsenoside F2 Initiates an Autophagic Progression in Breast Cancer Stem Cells; Somi Kim Cho Chapter 5. Role of Autophagy in Cancer Therapy; Ricardo Gargini Chapter 6. Autophagy in Human Brain Cancer. Therapeutic Implications; Clelia Miracco Chapter 7. Blockage of Lysosomal Degradation is Detrimental to Cancer Cells' Survival: Role of Autophagy Activation; Jessica L. Schwartz-Roberts Chapter 8. Induction of Protective Autophagy in Cancer cells by an NAE Inhibitor MLN4924; Yi Sun Chapter 9. Effect of Autophagy on Chemotherapy-induced Apoptosis and Growth Inhibition; Shanshan Zhang Chapter 10. Autophagy Upregulation Reduces Doxorubicin-induced Cardiotoxicity; Balindiwe J.N. Sishi III. Role of Autophagy in Cardiovascular, Metabolic, and Neurodegenerative Diseases Chapter 11. Autophagy in Critical Illness; Rajesh K. Aneja Chapter 12. Autophagy in the Onset of Atrial Fibrillation; Rodrigo Troncoso Chapter 13. Role of Autophagy in Atherogenesis; Peggy Robinet Chapter 14. Regulation of Autophagy in Insulin Resistance and Type 2 Diabetes; Monika Cahova Chapter 15. Pancreatic Beta Cell Autophagy and Islet Transplantation; Subbiah Pugazhenthi Chapter 16. Autophagy Guards against Immunosuppression and Renal Ischemia-Reperfusion Injury in Renal Transplantation; Yoshitaka Isaka Chapter 17. When the Good Turns Bad: Challenges in the Targeting of Autophagy in Neurodegenerative Diseases; Melissa Nassif Chapter 18. The -Tubulin Deacetylase HDAC6 in Aggresome formation and autophagy: Implications for neurodegeneration; Christiane Richter-Landsberg
Dr. Hayat has published extensively in the fields of microscopy, cytology, immunohistochemistry, immunocytochemistry, and antigen retrieval methods. He is Distinguished Professor, Department of Biological Sciences, Kean University, Union, New Jersey, USA.