Table of Contents

Unit I: Pathophysiologic Processes

1. Introduction to Pathophysiology

2. Homeostasis and Adaptive Responses to Stressors

Unit II: Cellular Function

3. Cell Structure and Function

4. Cell Injury, Aging, and Death

5. Genome Structure, Regulation, and Tissue Differentiation

6. Genetic and Developmental Disorders

7. Neoplasia

Unit III: Defense

8. Infectious Processes

9. Inflammation and Immunity

10. Alterations in Immune Function

11. Malignant Disorders of White Blood Cells

12. HIV Disease and AIDS

Unit IV: Oxygen Transport, Blood Coagulation, Blood Flow, and Blood Pressure

13. Alterations in Oxygen Transport

14. Alterations in Homeostasis and Blood Coagulation

15. Alterations in Blood Flow

16. Alterations in Blood Pressure

Unit V: Cardiac Function

17. Cardiac Function

18. Alterations in Cardiac Function

19. Heart Failure and Dysrhythmias: Common Sequelae of Cardiac Diseases

20. Shock

Unit VI: Respiratory Function

21. Respiratory Function and Alterations in Gas Exchange

22. Obstructive Pulmonary Disorders

23. Restrictive Pulmonary Disorders

Unit VII: Fluid, Electrolyte, and Acid-Base Homeostasis

24. Fluid and Electrolyte Homeostasis and Imbalances

25. Acid-Base Homeostasis and Imbalances

Unit VIII: Renal and Bladder Function

26. Renal Function

27. Intrarenal Disorders

28. Acute Kidney Injury and Chronic Kidney Disease

29. Disorders of the Lower Urinary Tract

Unit IX: Genital and Reproductive Function

30. Male Genital and Reproductive Function

31. Alterations in Male Genital and Reproductive Function

32. Female Genital and Reproductive Function

33. Alterations in Female Genital and Reproductive Function

34. Sexually Transmitted Infections

Unit X: Gastrointestinal Function

35. Gastrointestinal Function

36. Gastrointestinal Disorders

37. Alterations in Function of the Gallbladder and Exocrine Pancreas

38. Liver Diseases

Unit XI: Endocrine Function, Metabolism, and Nutrition

39. Endocrine Physiology and Mechanisms of Hypothalamic-Pituitary Regulation

40. Disorders of Endocrine Function

41. Diabetes Mellitus

42. Alterations in Metabolism and Nutrition

Unit XII: Neural Function

43. Structure and Function of the Nervous System

44. Acute Disorders of Brain Function

45. Chronic Disorders of Neurologic Function

46. Alterations in Special Sensory Function

47. Pain

Unit XIII: Neuropsychological Function

48. Neurobiology of Psychotic Illnesses

49. Neurobiology of Nonpsychotic Illnesses

Unit XIV: Musculoskeletal Support and Movement

50. Structure and Function of the Musculoskeletal System

51. Alterations in Musculoskeletal Function: Trauma, Infection, and Disease

52. Alterations in Musculoskeletal Function: Rheumatic Disorders

Unit XV: Integumentary System

53. Alterations in the Integumentary System

54. Burn Injuries

Appendix: Clinical and Laboratory Values