Scientists challenging dominant paradigms are either ignored or attacked by the scientific mainstream. This volume contains a selection of scientific papers presented at the two last GIRI meetings (International Research Group on Very Low Dose and High Dilution Effects). The majority of these papers present results performed with succussed high dilutions (homeopathic dilutions), even beyond the Avogrado number. All presented models are classified, and their interpretation is possible either in the mechanistic paradigm or in an information paradigm. This new field of research introduces new scientific concepts which are supported by experimental results. Furthermore, this nascent science is totally concerned with living organisms and, as such, it becomes necessary to define `information' brought by non-molecular high dilutions. This book presents brain-storming work of this research group and is one of the starting points of a scientific evolution.

Table of Contents

Preface. Introduction: The Perennial Challenge of Anomalies at the Frontiers of Science; B. Rubik. I: Hormesis. Radiation Hormesis; T.D. Luckey. Stimulation of Self-Recovery by Low Doses of Arsenite- Intoxicated Cells; F.A.C. Wiegant, et al. Stimulation of Cellular Self-Recovery by Application of the Similia- Principle; R. van Wijk, F.A.C. Wiegant. Preventive Effect of Monoclonal Anti-idiotypic Antibody Compared to a Hormetic Model on Rat Sarcoma; S. Faiderbe, et al. Evidence and Mechanistic Approach of the Protective Effects of Heavy Metal High Dilutions in Rodent and in Renal Cell Cultures; A. Delbancut, et al. II: In Vitro and in Vivo Models. From Stimulus to Message in Biological Systems, an Illustrated Survey; C. Bonne. Modification of 4 MHz N.M.R. Water Proton Relaxation Times in Very High Diluted Aqueous Solutions; J.L. Demangeat, et al. Dose- Dependence of the Various Functional Responses of Neutrophils to Formylpeptides; P. Bellavite, et al. The Role of the Bursa of Fabricius and Highly Dilute Bursin in Immunoendocrine Interactions in the Chickens; B.J. Youbicier-Simo, et al. Non-Molecular Information Transfer from Thyroxine to Frogs; P.C. Endler, et al. Pharmacodynamic Effects of Very High Dilutions of Belladonna on the Isolated Rat Duodenum; A. Cristea, et al. Chamomilla Homeopathic Dilution Effect on Central Nervous System; A. Cristea, et al. High Dilutions of Antigens Modulate the Immune Response to KLH; Z. Weisman, et al. Healing Chronic Wounds Performed on Mouse Ears Using Silica (Sio2) as a Homeopathic Remedy; M. Oberbaum, et al. III: Therapeutics and Provings. On Modelling Complex System Applied to Homeopathy. On Modelling Complex System: Wonderful but not Incomprehensible: J.L. Le Moigne. Contribution of Systemic Modelling to the Renewal of Homeopathic Theory Understood as a Complex Phenomenon; H. Carree. Effect of Belladonna 12CH and 30CH in Healthy Volunteers; H. Walach, et al. The Value of Using Homeopathy at the End of the Gestation in the Dog and Pig; Y. Grandmontagne, A. Riaucourt. Arsenicum Album and Neurotoxic Poisoning in Dogs and Cats; R. Blostin. Malaria and Homeopathic Remedies in Ghana; V.M.A. van Erp, M. Brands. AIDS and Integral Medicine; M. Brands. IV: Epistemologic Approach. Notes on Conceptual Basis of Science; A. Lagache. What is Information? A. Lagache. Index.