Introduction: The Gene Revolution
1: Natural Born Mutants
2: Supersize My Mouse
3: Light as a Life Tool
4: The Gene Scissors
5: Next Year's Models
6: The Molecular Farm
7: New Gene Therapy
8: Regenerating Life
9: Life as a Machine
Conclusion: A Redesigned Planet?
References
Index
John Parrington is an Associate Professor in Molecular and Cellular
Pharmacology at the University of Oxford, and a Tutorial Fellow in
Medicine at Worcester College, Oxford. He has published over 80
peer-reviewed articles in science journals including Nature,
Current Biology, Journal of Cell Biology, Journal of Clinical
Investigation, The EMBO Journal, Development, Developmental
Biology, and Human Reproduction. He has extensive experience
writing
popular science, having published articles in The Guardian, New
Scientist, Chemistry World, and The Biologist. He has also written
science reports for the Wellcome Trust, British Council, and Royal
Society. He is the
author of The Deeper Genome, (OUP, 2015).
A comprehensive digest of the extraordinary scientific material
relevant to the topic of gene editing. Parrington presents himself
as the trusted tour guide of the latest developments in this
rapidly advancing area of investigation.
*Science Magazine*
There is a revolution going on in the life sciences, one that has
already transformed scientific discovery and will soon change
medicine. It could even see us altering the ecosystem in a precise,
targeted way. This revolution has a name - CRISPR - and the key
part of John Parrington's Redesigning Life is a good summary of the
gene-editing technique that lies behind the acronym.
*Matthew Cobb, New Scientist*
A thorough and comprehensive account of the methodologies for
altering life that have been or are being developed, and the
directions that they may take in future.
*John Harris, Nature*
Parrington economically covers a huge swath of material, including
a discussion of artificial genetic materials, and successfully
communicates the excitement and relentless pace of the developments
in this field.
*Adrian Woolfson, Science*
painstakingly researched ... the examples themselves are clear,
concise and often arresting ... an engaging and comprehensive
introduction
*Thomas Christie Williams, LSE Business Review*
Parrington's clear descriptions and diagrams combined with
interesting snippets from the narrative and biography of scientific
discovery make the science behind these developments readily
accessible. Their relevance to our everyday lives is also
highlighted with Parrington continually drawing connections between
advances in the lab and their real world application.
*Socialist Review*
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