Her name was Henrietta Lacks, but scientists know her as HeLa. She was a poor black tobacco farmer who worked the same land as her slave ancestors, yet her cells - taken without her knowledge - become one of the most important tools in modern medicine. Taken in 1951, these cells became the first immortal human cell line ever grown in culture. They were vital for developing the polio vaccine; uncovered the secrets of cancer, viruses and the effects of the atom bomb; helped lead to important advances like in vitro fertilisation, cloning, and gene mapping, and have been bought and sold by the billions. Put together, her cells would now weigh more than 22 million tons and placed end-to-end would wrap around the earth five times. Now Rebecca Skloot takes us on an extraordinary journey, from the "coloured" wards of Johns Hopkins in the 1950s to poverty stricken tenements of East Baltimore today, where Henrietta's children are unable to afford health insurance, and struggle with feelings of pride, fear and betrayal. Their story is inextricably linked to the birth of bioethics, the rise of multi-billion dollar biotech industry, and the legal battles that determine if we own our bodies. Intimate in feeling, astonishing in scope, and impossible to put down, The Immortal Life of Henrietta Lacks captures the beauty and drama of scientific discovery, as well as its human consequences. About the AuthorRebecca Skloot is an award-winning science writer whose articles have appeared in the New York Times Magazine; O, The Oprah Magazine; Discover; Columbia Journalism Review; and elsewhere. She has also worked as a correspondent for National Public Radio and PBS. ReviewsThis distinctive work skillfully puts a human face on the bioethical questions surrounding the HeLa cell line. Henrietta Lacks, an African American mother of five, was undergoing treatment for cancer at Johns Hopkins University in 1951 when tissue samples were removed without her knowledge or permission and used to create HeLa, the first "immortal" cell line. HeLa has been sold around the world and used in countless medical research applications, including the development of the polio vaccine. Science writer Skloot, who worked on this book for ten years, entwines Lacks's biography, the development of the HeLa cell line, and her own story of building a relationship with Lacks's children. Full of dialog and vivid detail, this reads like a novel, but the science behind the story is also deftly handled. Verdict While there are other titles on this controversy (e.g., Michael Gold's A Conspiracy of Cells: One Woman's Immortal Legacy-and the Medical Scandal It Caused), this is the most compelling account for general readers, especially those interested in questions of medical research ethics. Highly recommended. [See Skloot's essay, p. 126; Prepub Alert, LJ 11/1/09.]-Carla Lee, Univ. of Virginia Lib., Charlottesville Copyright 2009 Reed Business Information. Science journalist Skloot makes a remarkable debut with this multilayered story about "faith, science, journalism, and grace." It is also a tale of medical wonders and medical arrogance, racism, poverty and the bond that grows, sometimes painfully, between two very different women-Skloot and Deborah Lacks-sharing an obsession to learn about Deborah's mother, Henrietta, and her magical, immortal cells. Henrietta Lacks was a 31-year-old black mother of five in Baltimore when she died of cervical cancer in 1951. Without her knowledge, doctors treating her at Johns Hopkins took tissue samples from her cervix for research. They spawned the first viable, indeed miraculously productive, cell line-known as HeLa. These cells have aided in medical discoveries from the polio vaccine to AIDS treatments. What Skloot so poignantly portrays is the devastating impact Henrietta's death and the eventual importance of her cells had on her husband and children. Skloot's portraits of Deborah, her father and brothers are so vibrant and immediate they recall Adrian Nicole LeBlanc's Random Family. Writing in plain, clear prose, Skloot avoids melodrama and makes no judgments. Letting people and events speak for themselves, Skloot tells a rich, resonant tale of modern science, the wonders it can perform and how easily it can exploit society's most vulnerable people. (Feb.) Copyright 2009 Reed Business Information. |